Observational studyBMC musculoskeletal disorders2025
Prevalence of osteoarthritis and clinical outcomes in patients with fractures of the tibial plateau - medium- and long-term analysis.
Observational study in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06451510 (Knee Osteoarthritis in the Region of Norrbotten), which is not on this map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Knee Osteoarthritis in the Region of Norrbotten (KORN)
Who cites it
6 citing papers in PubMed.
- [Treatment of tibial plateau fractures between the priorities of reconstruction and arthroplasty].Unfallchirurgie (Heidelberg, Germany) · 2026Review
- Tibial tubercle involvement in tibial plateau fractures is associated with nonunion, reoperation, and flexion deficits.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026Article
- Efficacy of 3D-printed bone graft container in the treatment of tibial plateau fractures and postoperative rehabilitation prediction model.BMC surgery · 2026Article
- Article
- The calcitonin receptor controls osteophyte formation, but not cartilage degeneration and subchondral bone loss in experimental osteoarthritis.Bone & joint research · 2026Article
- Medial Tibial Plateau Fractures and Fracture-Dislocations: A Mechanism-Based Narrative Review of Instability Patterns, Imaging, and Contemporary Management.Orthopedic reviews · 2026Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe incidence of post-traumatic osteoarthritis (OA) following intraarticular knee fractures has been estimated to be relatively high but it varies substantially between different reports. In this study we sought to assess the prevalence of radiographic knee OA secondary to tibial plateau fractures (TPF). The second aim was to report medium- and long-term functional outcomes and investigate whether there were any risk factors associated with these outcomes.
methodsWe retrospectively reviewed documentation of patients who had TPF between 2001 and 2015. The radiographs, clinical characteristics and patient-reported outcome measures (PROMs) scores were evaluated. Presence of radiographic OA was the primary endpoint. The other endpoints were the relationship between OA and different potential predictors as well as the scores in PROMs.
resultsThe study involved a total of 130 patients including 114 who were radiographically examined at mean follow-up time of 10 years (range 4.6-19.3 years). Radiographic OA was present in 50% of patients (34% in the injured knee and 16% in both knees). Having OA in the contralateral knee increased the odds to develop OA in the index knee (OR = 4.8; 95%CI 1.6-4.1 in the crude model and OR = 6.6; 95%CI 1.8-23.5 in the model adjusted for age, sex, BMI, fracture type and treatment method). The occurrence of OA was associated stronger with medial or bicondylar TPF than with lateral condyle TPF (OR = 2.8; 95%CI 1.2-6.1 in the crude model and OR = 3.4; 95%CI 1.4-8.6 in the adjusted model). The KOOS scores were significantly lower in patients with OA than in those without OA in the index knee in all the KOOS subscales (p < 0.007), except for the KOOS Symptoms (p = 0.362). The EQ-5D-5L index score was significantly higher in patients without OA in the index knee compared to those with OA (p = 0.015).
conclusionRadiographic OA following TPF occurred in 50% of knee joints. The odds for knee OA were highest after medial or bicondylar fractures. Patients with OA in the index knee had lower scores in both condition-specific and generic PROMs than subjects without OA, which indicates that TPF may contribute to the development of both OA disease and illness.
trial registrationThe trial was registered retrospectively on June 4, 2024 on ClinicalTrials.gov (registration number: NCT06451510).
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