Evidence map›Paper›PMID 40426115›Full record

ArticleBMC cancer2025

Deep learning network enhances imaging quality of low-b-value diffusion-weighted imaging and improves lesion detection in prostate cancer.

Zheng Liu, Wei-Jie Gu, Fang-Ning Wan, Zhang-Zhe Chen, Yun-Yi Kong, Xiao-Hang Liu, Ding-Wei Ye, Bo Dai

Abstract read
In one paragraph

Article in BMC cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zheng Liu *Department of Urology, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
Wei-Jie Gu *Department of Urology, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
Fang-Ning WanDepartment of Urology, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
Zhang-Zhe ChenDepartment of Oncology, Shanghai Medical College, Fudan University, 200032, Shanghai, China.
Yun-Yi KongDepartment of Oncology, Shanghai Medical College, Fudan University, 200032, Shanghai, China.
Xiao-Hang LiuDepartment of Oncology, Shanghai Medical College, Fudan University, 200032, Shanghai, China. 09111230002@fudan.edu.cn.
Ding-Wei YeDepartment of Urology, Fudan University Shanghai Cancer Center, Shanghai, 200032, China. dwyeli@163.com.
Bo DaiDepartment of Urology, Fudan University Shanghai Cancer Center, Shanghai, 200032, China. bodai1978@126.com.

Funding

National Natural Science Foundation of China 82303097National Natural Science Foundation of China 82373355Shanghai Anti-Cancer Association SACA-AX202302Shanghai Municipal Health Commission 2022XD013Shanghai Oriental Talent Program Top Project BJKJ2024007
6 · The paper itself

Abstract

backgroundDiffusion-weighted imaging with higher b-value improves detection rate for prostate cancer lesions. However, obtaining high b-value DWI requires more advanced hardware and software configuration. Here we use a novel deep learning network, NAFNet, to generate a deep learning reconstructed (DLR

methodsWe enrolled 303 prostate cancer patients with both 800 and 1500 b-values from Fudan University Shanghai Cancer Centre between 2017 and 2020. We assigned these patients to the training and validation set in a 2:1 ratio. The testing set included 36 prostate cancer patients from an independent institute who had only preoperative DWI at 800 b-value. Two senior radiology doctors and two junior radiology doctors read and delineated cancer lesions on DLR

resultsAfter training and generating, within junior radiology doctors, the diagnostic AUC based on DLR

conclusionsDLR

Indexed as

Deep LearningDiffusion Magnetic Resonance ImagingImage Interpretation, Computer-AssistedProstatic NeoplasmsAgedHumansMaleMiddle AgedDeep learningDiffusion–weighted imagingHigh b-ValueProstate CancerWhole-slide imaging.

Identifiers

PMID40426115
PMCPMC12117842

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.