SynthesisBMC pediatrics2025
Prevention of nasal injury in preterm infants during positive pressure ventilation: a systematic review of interface and dressing selection.
Synthesis in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Comparison of nasal interfaces and pressures during critical time-points in NICU: observation data from over 10 years.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- OcclusiveEuropean respiratory review : an official journal of the European Respiratory Society · 2026Review
- Incidence and Risk Factors of Nasal Pressure Injuries in Neonates Receiving Noninvasive Ventilation.Journal of clinical medicine · 2026Article
- Correction: Prevention of nasal injury in preterm infants during positive pressure ventilation: a systematic review of interface and dressing selection.BMC pediatrics · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo conduct a systematic review and meta-analysis comparing the incidence of nasal injury in preterm infants undergoing continuous positive airway pressure (CPAP) therapy using nasal masks versus nasal prongs, and to explore the potential effects of prophylactic use of hydrocolloid dressings in reducing nasal injury in preterm infants.
methodsOn March 1, 2025, we searched the Web of Science, PubMed, Cochrane, and Embase databases for measures and strategies to prevent nasal injury in preterm infants undergoing positive pressure ventilation, and collected relevant randomized controlled trials. The Cochrane Risk of Bias Assessment Tool was used to evaluate the risk of bias in the literature, and the modified Jadad score was used to assess the quality of the studies. Key information was extracted, including the characteristics of the study subjects, interventions, incidence and severity of nasal injury, and failure rate of positive pressure ventilation.
resultsA total of 12 studies met the inclusion and exclusion criteria, including 1 low-quality study and 11 high-quality studies, with a total sample size of 1,271 participants. Eight studies compared the effects of nasal prongs and nasal masks, with 3 studies investigating the effects of alternating use of nasal prongs and masks. Four studies used hydrocolloid dressings. The results of the meta-analysis showed that the overall incidence of nasal injury was 0.62 (95% CI 0.45-0.87, P = 0.006) in the nasal mask group, 0.95 (95% CI 0.27-3.29, P = 0.093) in the alternating use group, and 0.40 (95% CI 0.30-0.53, P < 0.0001) in the hydrocolloid dressing group.
conclusionThe incidence of nasal injury was lower in the nasal mask group compared to the nasal prong group. However, the effect of alternating use of nasal masks and prongs on reducing the incidence of nasal injury was not significant. Prophylactic use of hydrocolloid dressings had a significant effect on reducing the incidence of nasal injury in preterm infants. However, the limited number of existing studies and the small sample sizes of the included studies restricted the generalizability of the conclusions. Future research should further optimize the standardization of interventions and conduct multicenter, large-sample randomized controlled trials to promote continuous improvement in clinical nursing practice.
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