ArticleBMC pediatrics2025
Determinants of neonatal jaundice among neonates admitted to neonatal intensive care unit in hospitals of Gurage zone, Southern Ethiopia.
Article in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- TabPFN-based explainable machine learning for predicting neonatal hyperbilirubinemia: A decade-long retrospective cohort study.Medicine · 2026Article
- A 10-year retrospective assessment of prevalence and factors associated with jaundice among neonates in selected facilities in Ondo State.BMC pediatrics · 2026Article
- Clinical outcomes and determinants of neonatal hyperbilirubinemia among NICU admissions: a retrospective study in Ethiopia.Scientific reports · 2026Article
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4 authors.
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Abstract
introductionNeonatal jaundice is the discoloration of the skin, sclera, and mucosa resulting from an excessive accumulation of bilirubin within the tissue and plasma. Every year, around 1.1 million newborn babies worldwide experience severe hyperbilirubinemia and the majority reside in Sub-Saharan Africa and South Asia. Evidences on determinants of neonatal jaundice are limited in Ethiopia, particularly in our study area.
objectiveTo identify the determinants of neonatal jaundice among neonates admitted to neonatal intensive care unit in hospitals of Gurage zone, Southern Ethiopia, 2022.
methodHospital-based unmatched retrospective case-control study was employed by reviewing one-year medical record of neonates from June 1, 2021 to May 30, 2022 in Gurage zone selected hospitals. The sample size was calculated by using Epi Info version 7 and study participants were selected by using a simple random sampling technique. Data were collected through a data extraction format. The data was entered using Epi data version 3.2 and exported to SPSS version 25 for analysis. Bivariate and multivariable logistic regression analysis were employed at 95% confidence interval for the existence of the association. P-value < 0.05 was used to identify the level of statistical significance.
resultIn this study, 375 neonatal medical charts which includes 125 cases and 250 controls were input into the data analysis process. Neonatal sepsis (AOR: 2.38; with 95% CI: 1.35-4.17), cephalic hematoma (AOR: 4.92; with 95% CI: 2.61-9.26), polycythemia (AOR: 3.60; with 95% CI: 2.03-6.34), prematurity (AOR: 4.57; 95% CI: 2.45-8.49), birth asphyxia (AOR: 2.26; 95% CI: 1.27-4.02), and breastfeeding (AOR: 5.35; 95% CI: 1.90-15.0) were the determinants of NNJ.
conclusionThis study identifies preterm birth, newborn polycythemia, birth asphyxia, neonatal sepsis, breastfeeding, and cephalic hematoma as significant determinant factors in neonatal jaundice.
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