Evidence map›Paper›PMID 40426068›Full record

ReviewBMC pediatrics2025

The term cotwin with spatial pulmonary lesions and elevated maternal-neonatal D-dimer levels following single intrauterine fetal death in a monochorionic-monoamniotic twin pregnancy: a case report and literature review.

Haiyan Liu, Xiaoyue Zhang, Zhenzhen Liu, Yi Yu, Weirong Gu

Abstract readCase ReportsReview
PubMed Full text at PMC Publisher
In one paragraph

Review in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Haiyan Liu *Department of Obstetrics, Obstetrics and Gynecology Hospital of Fudan University, 419 Fangxie Road, Huangpu District, Shanghai, China.
Xiaoyue Zhang *Department of Obstetrics, Obstetrics and Gynecology Hospital of Fudan University, 419 Fangxie Road, Huangpu District, Shanghai, China.
Zhenzhen LiuDepartment of Obstetrics, Obstetrics and Gynecology Hospital of Fudan University, 419 Fangxie Road, Huangpu District, Shanghai, China.
Yi YuDepartment of Obstetrics, Obstetrics and Gynecology Hospital of Fudan University, 419 Fangxie Road, Huangpu District, Shanghai, China.
Weirong GuDepartment of Obstetrics, Obstetrics and Gynecology Hospital of Fudan University, 419 Fangxie Road, Huangpu District, Shanghai, China. guweirong@fudan.edu.cn.

Funding

the National Natural Science Foundation of China 81801469
6 · The paper itself

Abstract

backgroundComplications such as cerebral impairment, preterm delivery, and even intrauterine death can occur in monochorionic twin pregnancies with singleton fetal death. The coagulation functions of the surviving fetus and mother remain controversial. CASE PRESENTATION: We reported a case of spontaneous single intrauterine fetal death at 17 weeks of gestation in a monochorionic monoamniotic twin pregnancy, followed by increased maternal and neonatal D-dimer levels and spatial pulmonary lesions in the surviving term cotwin, without cerebral impairment. The mother experienced significant postpartum pelvic hematoma, which was managed with conservative treatment and resolved.

conclusionsMonitoring maternal and neonatal D-dimer, along with a detailed examination of the respiratory system and brain impairment of the surviving cotwin and newborn, maybe is crucial. This could be especially relevant in monochorionic monoamniotic twin pregnancies complicated by placental arterio-arterial or veno-venous anastomoses and elevated maternal D-dimer levels.

Indexed as

Fetal DeathFibrin Fibrinogen Degradation ProductsPregnancy, TwinAdultFemaleHematomaHumansInfant, NewbornPregnancyTwins, MonozygoticFibrin Fibrinogen Degradation Productsfibrin fragment DD-dimerMonochorionic monoamniotic twin pregnancyPlacental anastomosesPulmonary lesionSpontaneous single intrauterine fetal death

Identifiers

PMID40426068
PMCPMC12108043

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.