ArticleBMC geriatrics2025
Prevalence of sarcopenia and its association with frailty and malnutrition among older patients with sepsis-a cross-sectional study in the emergency department.
Article in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Impact of sarcopenia and frailty on outcomes of patients with sepsis or septic shock: a systematic review and meta-analysis.Frontiers in nutrition · 2025Pooled it
- Sepsis in Frail Older Adults: Tailored Antimicrobial Stewardship and Individualized Care Approach.Antibiotics (Basel, Switzerland) · 2026Review
- Association between hospital frailty risk score and in-hospital mortality in critically ill patients with sepsis: results from MIMIC-IV database.Scientific reports · 2026Article
- Sarcopenia and sepsis fuel a self-perpetuating cycle of immunometabolism decline.Frontiers in immunology · 2026Review
- The red cell distribution width to albumin ratio as a novel biomarker for predicting short-term mortality in severe pulmonary sepsis: a retrospective study with dual-cohort validation.Frontiers in medicine · 2026Article
- Red cell distribution width to albumin ratio predicts short-term mortality in urosepsis: a dual-cohort study.Frontiers in nutrition · 2026Article
- Relationship of the Endothelial Activation and Stress Index with 28-day mortality in urosepsis patients: a retrospective two-cohort investigation.Frontiers in medicine · 2026Article
- Retrospective Analysis of the Association Between Sarcopenia and Fall Risk in Older Breast Cancer Patients Using Real World Data (TriNetX).Cancer medicine · 2025Article
- Article
- Association between the geriatric nutritional risk index and 28-day mortality in critically ill sepsis-associated pneumonia patients: retrospective study based on two cohorts.Frontiers in nutrition · 2025Article
- The relationship between improved elderly nutritional risk index and short-term all-cause mortality in patients with urinary sepsis: a retrospective cohort study.Frontiers in nutrition · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStudies on the prevalence of sarcopenia and its relationship with other geriatric syndromes among older patients with sepsis in the emergency department (ED) are scarce. This study aimed to investigate the prevalence of sarcopenia among older patients with sepsis and explore its association with specific geriatric symptoms: frailty and malnutrition.
methodsThis cross-sectional study was carried out in China from January to November 2022. Muscle mass, as indicated by the skeletal muscle index (SMI) was measured using abdominal plain computed tomography. Sarcopenia, frailty, and nutritional status were defined according to the Asian Working Group for Sarcopenia 2019 criteria, Clinical Frailty Scale (CFS) score, and Mini Nutritional Assessment-Short Form (MNA-SF) score. The correlations of the SMI with the CFS and MNA-SF scores were analyzed using nonparametric Spearman correlation analysis. Univariate and multivariable logistic regression analyses were performed to determine the associations of sarcopenia with frailty and malnutrition.
resultsA total of 602 patients (332 men; median age, 78 years; median body mass index, 23.1 kg/m
conclusionsSarcopenia and coexisting geriatric syndromes were prevalent and interrelated among older patients with sepsis in EDs. Clinicians should assess older patients with sepsis for geriatric syndromes to provide them with more accurate interventions.
trial registrationThis study was registered at www.chictr.org.cn (registration number: ChiCTR2300070377, date: 11-04-2023).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.