ArticleBMC microbiology2025
Gut microbiota and relevant metabolites analysis in perianal abscess of infants.
Article in BMC microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Characteristic alterations of gut microbiota and metabolites in patients with perianal abscess: a multi-omics analysis.Frontiers in microbiology · 2025Article
- Microbial profile and putative microbial origin of anorectal abscess based on 16S rDNA sequencing.Frontiers in cellular and infection microbiology · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
objectivesTo explore the characteristics of the gut microbiota and metabolites in infants with perianal abscess compared with healthy infants, thereby providing a reference for treating perianal abscess in infants.
methodsThe gut microbiota of 19 infants with perianal abscess and 21 healthy infants were compared using 16S rRNA gene sequencing. Metabolite compositions were compared between a subset of 16 infants with perianal abscess and 8 healthy infants.
resultsBoth groups showed significant differences in the abundance of the genera Ruminococcus (P = 0.002) and Parasutterella (P = 0.004). Five metabolic pathways, namely, steroid biosynthesis, one-carbon pool by folate, synthesis, secretion, and action of the parathyroid hormone, cholesterol metabolism, and tuberculosis, were significantly enriched. Three metabolites, namely, calcidiol, dihydrofolic acid, and taurochenodesoxycholic acid, were involved in these enriched pathways.
conclusionThe study revealed significant differences in the composition of the gut microbiota and metabolites between healthy infants and those with perianal abscess, suggesting a potential association between the gut microbiota and infantile perianal abscess.
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Registered trials
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