ArticleMikrochimica acta2025
A neuraminidase-based electrochemical biosensor for high-throughput screening of antiviral compounds in traditional Chinese medicine.
Article in Mikrochimica acta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A visualization analysis of Traditional Chinese Medicine for influenza prevention and treatment: advances, hotspots, and future trends.Frontiers in medicine · 2026Pooled it
- Research Progress and Screening Strategies of Natural Product-Derived Neuraminidase Inhibitors.Biosensors · 2026Review
- Innovative Biosensor Platforms for the Detection of Metformin in Diabetes Management.International journal of analytical chemistry · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neuraminidase (NA), a highly sensitive recognition element for anti-influenza activity, was immobilized on a glassy carbon electrode modified with nitrogen-doped graphene-functionalized multi-walled carbon nanotube composites (N-Gr/MWCNTs) and polypyrrole (Ppy) via re-polymerization. A highly sensitive electrochemical biosensor was thus developed for the rapid screening of antiviral components in natural products, utilizing the high specific surface area and conductivity of N-Gr/MWCNTs and polypyrrole, along with the high-throughput and specific recognition capabilities of NA. Under optimized conditions, the sensor was used to assess five distinct classes of compounds, demonstrating an activity sequence of Baicalein > Baicalin > Rutin ≈ Matrine > Levistilide A, which aligns with previous literature. This study presents a convenient and efficient method for screening antiviral components in natural products, providing new strategies and technological support for the development of cost-effective, eco-friendly, and rapid screening platforms.
Indexed as
Identifiers
40425963What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.