Evidence map›Paper›PMID 40425949›Full record

ArticlePhotochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology2025

Investigation of singlet oxygen quantum yield of protonated water-soluble glycosylated porphyrin photosensitizer for photodynamic therapy.

Sekar Monisha, Samuthirakani Ajithkumar, Thangavel Myithili, Kumaresan Sudharsan, Thangaraj Keerthana, Baskaran Sarikalakshmi, Venkatesh Soundharya, Mohan Pandi, Palanisamy Kalimuthu

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Article in Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sekar Monisha *Department of Chemistry, The Gandhigram Rural Institute-Deemetd to be University, Gandhigram, Dindigul, Tamilnadu, 624302, India.
Samuthirakani Ajithkumar *Department of Chemistry, The Gandhigram Rural Institute-Deemetd to be University, Gandhigram, Dindigul, Tamilnadu, 624302, India.
Thangavel MyithiliSchool of Biotechnology, Madurai Kamaraj University, Madurai, Tamilnadu, India.
Kumaresan SudharsanDepartment of Chemistry, The Gandhigram Rural Institute-Deemetd to be University, Gandhigram, Dindigul, Tamilnadu, 624302, India.
Thangaraj KeerthanaDepartment of Chemistry, The Gandhigram Rural Institute-Deemetd to be University, Gandhigram, Dindigul, Tamilnadu, 624302, India.
Baskaran SarikalakshmiDepartment of Chemistry, The Gandhigram Rural Institute-Deemetd to be University, Gandhigram, Dindigul, Tamilnadu, 624302, India.
Venkatesh SoundharyaDepartment of Chemistry, The Gandhigram Rural Institute-Deemetd to be University, Gandhigram, Dindigul, Tamilnadu, 624302, India.
Mohan PandiSchool of Biotechnology, Madurai Kamaraj University, Madurai, Tamilnadu, India.
Palanisamy KalimuthuDepartment of Chemistry, The Gandhigram Rural Institute-Deemetd to be University, Gandhigram, Dindigul, Tamilnadu, 624302, India. pakalimuthu@gmail.com.ORCID http://orcid.org/0000-0003-2557-7781

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we explored the photophysical properties of three forms of glycosylated porphyrin photosensitizers, mainly focusing on their ability to generate singlet oxygen for photodynamic therapy. Porphyrin derivatives are known for their efficacy in photodynamic therapy due to their ability to generate singlet oxygen, a reactive oxygen species crucial for cellular damage in cancer therapy. The three porphyrin molecules are designated as free-base (GPPOH), protonated (PGPPOH), and metalated (ZnGPPOH) glycosylated porphyrins. The singlet oxygen quantum yield (Φ

Indexed as

PhotochemotherapyPhotosensitizing AgentsPorphyrinsProtonsSinglet OxygenApoptosisCell SurvivalGlycosylationHEK293 CellsHeLa CellsHumansMolecular StructureSolubilityWaterPhotosensitizing AgentsPorphyrinsProtonsSinglet OxygenWaterGlycosylated porphyrinPhotodynamic therapyPhoto-physical studiesPhotosensitizerSinglet oxygen quantum yield

Identifiers

PMID40425949

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.