ArticleSurgical endoscopy2025
Surgery combined endoscopic stricturotomy for deep small bowel strictures from Crohn' disease: a prospective, single-center cohort study of a novel approach.
Article in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Cost-Effectiveness of Endoscopic Stricturotomy Versus Resection Surgery for Crohn's Disease Strictures.Healthcare (Basel, Switzerland) · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
BACKGROUND AND
aimsA common complication which can influence the prognosis of Crohn's disease (CD) is multi-segmental strictures, and there are limitations to using either surgical or endoscopic treatment alone. We aimed to treat multi-segmental strictures in CD using combination of surgery and endoscopic therapy and to evaluate the efficacy and safety of conventional surgery combined with endoscopic stricturotomy for the treatment of deep small bowel multi-segmental fibrotic strictures.
methods21 patients with CD who underwent conventional surgery combined with endoscopic stricturotomy between January 2020 and December 2023 were included. Outcomes included immediate technical success, short- and long-term clinical efficacy, risk factors assessment, and analysis of adverse events. No risk factors were identified that would predict re-intervention.
resultsThe overall immediate success rate of the combined technique was 100%, with a 98.4% success rate for the endoscopic procedure alone. 85.7% of patients showed significant improvement in obstructive symptoms compared to the previous period, and only 9.5% required enteral nutrition, with the remainder resuming a regular diet by 8 weeks (all P < 0.0001). The median follow-up of the 21 patients was 528 days (IQR, 404-1296), with a one-year no re-intervention rate of 81.7% (95% CI, 70.6-90.2%). The incidence of adverse events of the procedure was 19%, 14% bleeding and 5% perforation, but all could be managed with intraoperative interventions without the need for postoperative re-intervention.
conclusionsSurgery combined with endoscopic stricturotomy is a safe and effective treatment of multi-segmental fibrotic strictures in CD may provide a novel treatment option for strictures in CD.
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Registered trials
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