Evidence map›Paper›PMID 40425644›Full record

ArticleScientific reports2025

The influence of habitual tooth brushing frequency on individuals diagnosed with coronary artery disease.

Zihan Tang, Tian Qiu, Runfeng Ma, Ruoyu Wang, Bingqian Wang, Yiduo Lu, Bi Huang, Suxin Luo, Gang Liu

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zihan Tang *Chongqing Medical University, Chongqing, China.
Tian Qiu *Chongqing Medical University, Chongqing, China.
Runfeng MaChongqing Medical University, Chongqing, China.
Ruoyu WangChongqing Medical University, Chongqing, China.
Bingqian WangChongqing Medical University, Chongqing, China.
Yiduo LuNaval Medical University, Shanghai, China.
Bi HuangDepartment of Cardiovascular Medicine, Cardiovascular Research Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Suxin LuoDepartment of Cardiovascular Medicine, Cardiovascular Research Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Gang LiuDepartment of Cardiovascular Medicine, Cardiovascular Research Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. 203745@hospital.cqmu.edu.cn.ORCID http://orcid.org/0000-0003-4368-5671

Funding

the CQMU Program for Youth Innovation in Future Medicine W0010the "Tomorrow Cup" Education and Teaching Reform Research of International Medical College, Chongqing Medical University 2023-01
6 · The paper itself

Abstract

Coronary artery disease (CAD) is a prevalent and high-mortality condition globally. The awareness regarding adequate oral care in China was insufficient. This study investigates the outcomes of CAD patients in southwest China based on their tooth brushing frequency. A total of 841 CAD patients were selected from a cohort of 32,709 residents. Over a four-year follow-up period, the incidence of three-point major adverse cardiovascular events (3P-MACEs) was evaluated. The results indicated that the hazard ratios (HR) with 95% confidence intervals (CIs) for 3P-MACEs among the three groups of tooth brushing frequency (twice, once, and thrice daily) were: reference, 1.61 (1.09-2.37) (p = 0.017), and 0.49 (0.15-1.62) (p = 0.241). Patients who brushed their teeth only once a day had a 1.71 (1.18-2.46) times higher risk compared to those who brushed twice or more daily (p = 0.004). In conclusion, insufficient tooth brushing frequency appears to be associated with a higher risk of adverse outcomes among CAD patients.

Indexed as

Coronary Artery DiseaseToothbrushingAgedChinaFemaleHumansIncidenceMaleMiddle AgedRisk FactorsCoronary artery diseaseSouthwest ChinaThree-point major adverse cardiovascular eventsTooth brushing frequency

Identifiers

PMID40425644
PMCPMC12116763

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.