Evidence map›Paper›PMID 40425558›Full record

ArticleNature communications2025

Blood-triggered self-sealing and tissue adhesive hemostatic nanofabric.

Yan Fang, Linyu Wang, Xinwei Zheng, Peng Ni, Zhibo Xu, Ziying Wang, Yunxiang Weng, Qinhui Chen, Haiqing Liu

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
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  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yan Fang *College of Chemistry and Materials Science, Fujian Key Laboratory of Polymer Materials, Fujian Normal University, Fujian, China.
Linyu Wang *College of Chemistry and Materials Science, Fujian Key Laboratory of Polymer Materials, Fujian Normal University, Fujian, China.
Xinwei ZhengCollege of Chemistry and Materials Science, Fujian Key Laboratory of Polymer Materials, Fujian Normal University, Fujian, China.
Peng NiCollege of Chemistry and Materials Science, Fujian Key Laboratory of Polymer Materials, Fujian Normal University, Fujian, China.
Zhibo XuCollege of Chemistry and Materials Science, Fujian Key Laboratory of Polymer Materials, Fujian Normal University, Fujian, China.
Ziying WangCollege of Chemistry and Materials Science, Fujian Key Laboratory of Polymer Materials, Fujian Normal University, Fujian, China.
Yunxiang WengCollege of Chemistry and Materials Science, Fujian Key Laboratory of Polymer Materials, Fujian Normal University, Fujian, China.
Qinhui ChenCollege of Chemistry and Materials Science, Fujian Key Laboratory of Polymer Materials, Fujian Normal University, Fujian, China. chenqh@fjnu.edu.cn.ORCID http://orcid.org/0000-0002-5377-4136
Haiqing LiuCollege of Chemistry and Materials Science, Fujian Key Laboratory of Polymer Materials, Fujian Normal University, Fujian, China. haiqingliu@fjnu.edu.cn.ORCID http://orcid.org/0000-0003-4457-6848

Funding

National Natural Science Foundation of China (National Science Foundation of China) 22175037
6 · The paper itself

Abstract

Current hemostatic fabric often encounters the issue of blood seeping or leaking through the fabric and at the junctions between the fabric and tissue, leading to extra blood loss. Herein, we report a hemostatic nanofabric composed of anionic and cationic nanofibers. Upon contact with wound, the porous nanofabric can absorb the interfacial blood and self-seal to form a compact physical barrier through interfiber bonding, preventing blood from longitudinally penetrating the fabric. This process results in the encapsulation of blood components within the electrostatically crosslinked nanofiber network, creating a robust thrombus that reinforces the physical barrier. Moreover, this nanofabric exhibits strong tissue adhesiveness, inhibiting blood seeping out at the seam of the fabric and tissue. Its hemostatic performance in animal injuries surpasses that of standard cotton gauze and Combat Gauze

Indexed as

HemostaticsNanofibersTissue AdhesivesAnimalsFemoral ArteryHemostasisHumansMaleSwineWound HealingHemostaticsTissue Adhesives

Identifiers

PMID40425558
PMCPMC12116861

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.