Evidence map›Paper›PMID 40425508›Full record

ArticleThe Journal of organic chemistry2025

Nucleophilic Substitution of 1,3-Diiodobicyclo[1.1.1]pentane: Synthesis of Bicyclo[1.1.1]pentylpyridinium, Quinolinium, Isoquinolinium, and Pyrazolium Salts.

Harvey J C Monroe, Dolapo J Bello, Bradley J Duff, Mark R J Elsegood, Kohei Watanabe, Gareth J Pritchard, Marc C Kimber

Abstract read
In one paragraph

Article in The Journal of organic chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Harvey J C MonroeDepartment of Chemistry, School of Science, Loughborough University, Ashby Road, Loughborough LE11 3TU, U.K.
Dolapo J BelloDepartment of Chemistry, School of Science, Loughborough University, Ashby Road, Loughborough LE11 3TU, U.K.
Bradley J DuffDepartment of Chemistry, School of Science, Loughborough University, Ashby Road, Loughborough LE11 3TU, U.K.
Mark R J ElsegoodDepartment of Chemistry, School of Science, Loughborough University, Ashby Road, Loughborough LE11 3TU, U.K.ORCID 0000-0002-8984-4175
Kohei WatanabeFaculty of Education, Chiba University, 1-33, Yayoi-cho, Inage-ku, Chiba 263-8522, Japan.ORCID 0000-0002-3146-5439
Gareth J PritchardDepartment of Chemistry, School of Science, Loughborough University, Ashby Road, Loughborough LE11 3TU, U.K.ORCID 0000-0002-2925-1722
Marc C KimberDepartment of Chemistry, School of Science, Loughborough University, Ashby Road, Loughborough LE11 3TU, U.K.ORCID 0000-0003-2943-1974

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we describe the synthesis of bicyclo[1.1.1]pentane salts by the nucleophilic reaction of 1,3-diodobicyclo[1.1.1]pentane (DIBCP) with several classes of nucleophiles. The bicyclo[1.1.1]pentane fragments are established isosteres for

Identifiers

PMID40425508
PMCPMC12172055

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.