Evidence map›Paper›PMID 40425243›Full record

ArticleBMJ open2025

Knowledge, attitudes and practices relating to nutritional support and immune-related adverse events among patients undergoing immunotherapy for liver cancer: cross-sectional study.

Wen Wen, Yingshuang Chen, Fangqing Gao, Liling Tong

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Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Wen WenHepatobiliary and Pancreatic Surgery, Affiliated Haikou Hospital of Xiangya Medical College, Central South University, Haikou, China.
Yingshuang ChenHepatobiliary and Pancreatic Surgery, Affiliated Haikou Hospital of Xiangya Medical College, Central South University, Haikou, China.
Fangqing GaoGastroenterology Department, Affiliated Haikou Hospital of Xiangya Medical College, Central South University, Haikou, China 13876780494@163.com.ORCID http://orcid.org/0009-0008-6025-7445
Liling TongNursing Department, Affiliated Haikou Hospital of Xiangya Medical College, Central South University, Haikou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo examine the knowledge, attitude and practice (KAP) regarding immune-related adverse events (irAEs) and nutritional support among patients with liver cancer (LC).

designCross-sectional study.

settingRecruitment was carried out at Haikou People's Hospital, Haikou, China, from December 2022 to April 2023.

participantsPatients undergoing immunotherapy for LC. PRIMARY AND SECONDARY OUTCOME MEASURES: Mean knowledge, attitudes, practices, and lifestyle scores were assessed using an investigator-designed questionnaire completed by patients during immunotherapy.

resultsThe study included 402 participants. The mean knowledge, attitudes, practices and lifestyle scores were 6.60±3.51 (/10, 66.00%), 41.26±5.06 (/50, 82.52%), 30.74±4.20 (/40, 76.85%) and 42.37±6.04 (/55, 77.04%), respectively. Attitude scores were associated with practice scores (β=0.381, p<0.001) and lifestyle (β=1.928, p<0.001). Urban residence was associated with higher attitude scores (β=1.242, p=0.013). Living with someone was associated with a higher attitude score (β=1.619, p=0.044). More than one immunotherapy line was associated with a higher lifestyle score (β=1.928, p<0.001). Finally, the female gender was associated with a lifestyle score (β=1.431, p=0.023).

conclusionPatients with LC and undergoing immunotherapy had moderate KAP towards irAEs and nutritional support. They also displayed moderate lifestyle scores. Urban residents, people not living alone, females and those having received two or more immunotherapy treatments were positively associated with attitude, while attitude was positively associated with practice and lifestyle.

Indexed as

Health Knowledge, Attitudes, PracticeImmunotherapyLiver NeoplasmsNutritional SupportAdultAgedChinaCross-Sectional StudiesFemaleHumansLife StyleMaleMiddle AgedSurveys and QuestionnairesCross-Sectional StudiesHepatobiliary tumoursONCOLOGYPUBLIC HEALTH

Identifiers

PMID40425243
PMCPMC12107570

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.