Evidence map›Paper›PMID 40425226›Full record

Trial reportGut and liver2025

Early versus Late Eradication of

Cheal Wung Huh, Da Hyun Jung, Jie-Hyun Kim, Hyojin Park, Young Hoon Youn

Abstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in Gut and liver, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Cheal Wung HuhDepartment of Internal Medicine, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, Korea.ORCID 0000-0001-7327-8503
Da Hyun JungDepartment of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID 0000-0001-6668-3113
Jie-Hyun KimDepartment of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID 0000-0002-9198-3326
Hyojin ParkDepartment of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID 0000-0002-5759-5135
Young Hoon YounDepartment of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID 0000-0002-0071-229X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/Aims: Methods: In this multicenter, prospective, randomized trial, 191 patients undergoing ESD for gastric neoplasms were randomly assigned to either an early (3 to 5 days) or late (8 to 9 weeks) eradication group after ESD. The primary outcome was the rate of successful Results: A total of 149 patients were included in the per-protocol analysis (75 in the early eradication group and 74 in the late eradication group) after excluding patients who required surgery or were lost to follow-up. The early eradication group showed a significantly higher eradication rate compared to the late eradication group (early 80.0%, late 64.9%; p=0.045). However, the tolerability and side effects of the eradication therapy did not differ between the groups. In multivariate analysis, early initiation of eradication therapy after ESD was an independent predictor of successful eradication (odds ratio, 2.30; 95% confidence interval, 1.04 to 5.05; p=0.038). Conclusions: Early attempts to eradicate

Indexed as

Anti-Bacterial AgentsEndoscopic Mucosal ResectionHelicobacter InfectionsHelicobacter pyloriStomach NeoplasmsAgedFemaleHumansMaleMiddle AgedProspective StudiesTime FactorsTreatment OutcomeAnti-Bacterial AgentsEndoscopic submucosal dissectionGastric neoplasms

Identifiers

PMID40425226
PMCPMC12616143

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.