Evidence map›Paper›PMID 40425050›Full record

ReviewOpen biology2025

Beyond pathogenicity: the immunomodulatory role of the type III secretion system in beneficial plant-microbe interactions.

Iva Atanasković, Marija Nedeljković, Jelena Lozo

Abstract readReview
In one paragraph

Review in Open biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Secondary Metabolites ofPlants (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Iva AtanaskovićUniversity of Belgrade Faculty of Biology, Beograd, Serbia.ORCID 0000-0002-7028-1317
Marija NedeljkovićUniversity of Belgrade Faculty of Biology, Beograd, Serbia.
Jelena LozoUniversity of Belgrade Faculty of Biology, Beograd, Serbia.

Funding

International Centre for Genetic Engineering and Biotechnology CRP/SRB23-04_ECMinistry of Science, Technological Development and Innovation of the Republic of Serbia 451-03-137/2025-03/200178, 451-03-136/2025-03/200178
6 · The paper itself

Abstract

The type III secretion system (T3SS) has traditionally been studied for its role in bacterial virulence. However, recent research emphasizes its dual role in beneficial interactions between bacteria and plants. This review examines the immunomodulatory functions of T3SS beyond pathogenicity and focuses on how T3SS effectors manipulate plant immune responses to promote symbioses. By comparing T3SS mechanisms in pathogenic and non-pathogenic bacteria, we aim to understand how this system enables beneficial microbes to colonize plants and improve plant growth and stress resilience. We also investigate the potential of T3SS to trigger induced systemic resistance in plants, a mechanism that could be utilized in agriculture to improve crop resistance to pathogens. The review concludes with an outlook on future research and emphasizes the need for comprehensive studies on T3SS effectors in non-pathogenic bacteria and their interactions with plant hosts.

Indexed as

BacteriaHost-Pathogen InteractionsPlantsType III Secretion SystemsPlant DiseasesPlant ImmunitySymbiosisVirulenceType III Secretion Systemseffector proteinsimmunomodulationinduced systemic resistanceplant–microbe symbiosistype III secretion system

Identifiers

PMID40425050
PMCPMC12115841

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.