Evidence map›Paper›PMID 40424403›Full record

ArticlePloS one2025

High prevalence of low-concentration antimicrobial residues in commercial fish: A public health concern in Bangladesh.

Md Raihan Khan Nayem, Md Rahim Badsha, Md Kaisar Rahman, Shahneaz Ali Khan, Md Mazharul Islam, Md Latiful Bari, John I Alawneh, Ricardo J Soares Magalhaes, Mohammad Mahmudul Hassan

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Md Raihan Khan NayemRemount Veterinary and Farm Corps, Bangladesh Army, Dhaka, Bangladesh.ORCID https://orcid.org/0000-0001-5468-4178
Md Rahim BadshaFaculty of Veterinary Medicine, Chattogram Veterinary and Animal Sciences University, Chattogram, Bangladesh.
Md Kaisar RahmanFaculty of Veterinary Medicine, Chattogram Veterinary and Animal Sciences University, Chattogram, Bangladesh.
Shahneaz Ali KhanFaculty of Veterinary Medicine, Chattogram Veterinary and Animal Sciences University, Chattogram, Bangladesh.
Md Mazharul IslamDepartment of Animal Resources, Ministry of Municipality, Doha, Qatar.ORCID https://orcid.org/0000-0002-7357-9645
Md Latiful BariCenter for Advanced Research in Sciences, University of Dhaka, Dhaka, Bangladesh.
John I AlawnehPlant Biosecurity and Product Integrity, Biosecurity Queensland, Department of Primary Industries, Brisbane, Australia.
Ricardo J Soares MagalhaesQueensland Alliance for One Health Sciences, School of Veterinary Science, The University of Queensland, Gatton, Queensland, Australia.ORCID https://orcid.org/0000-0001-9157-8470
Mohammad Mahmudul HassanFaculty of Veterinary Medicine, Chattogram Veterinary and Animal Sciences University, Chattogram, Bangladesh.ORCID https://orcid.org/0000-0001-6495-4637

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotics are widely used in commercial fish farms in Bangladesh for therapeutic and prophylactic purpose, raising concerns about antimicrobial resistance (AMR) and environmental contamination. This study used Thin Layer Chromatography to detect antimicrobial residues in four commercially available fish species- Tilapia (Oreochromis aureus), Stinging catfish (Heteropneustes fossilis), Climbing perch (Anabas testudineus), and Pabda (Ompok pabda)-with 100 samples per species. Ultra High-Performance Liquid Chromatography quantified residues in a subset of 25 samples per species. The prevalence of Ciprofloxacin, Oxytetracycline, and Chlortetracycline residues varied significantly among fish species, with the highest prevalence observed for Ciprofloxacin in Tilapia (42%), Oxytetracycline in Pabda (41%), and Chlortetracycline in Tilapia (49%). Additionally, the prevalence of Levofloxacin and Chlortetracycline differed by sampling location, with the highest levels found in Jhawtala market, 27.5% for Levofloxacin and 53.8% for Chlortetracycline. Furthermore, residue concentrations were highest for Enrofloxacin in Climbing perch (69.32 µg/Kg) and Oxytetracycline in Pabda (88.73 µg/Kg). The highest Hazard Quotient (HQ) was for Enrofloxacin in Climbing perch (0.480), followed by Pabda (0.460), Stinging catfish (0.420), and Tilapia (0.387). While the HQ values were below 1.0, indicating no immediate toxicological risk, residues raise public health concerns due to the chance of potential AMR development. Further research is needed on antimicrobial bioaccumulation, indirect exposure sources, environmental contamination, and antimicrobial resistance in aquaculture and wild fish.

Indexed as

Anti-Bacterial AgentsAnti-Infective AgentsDrug ResiduesFishesFood ContaminationWater Pollutants, ChemicalAnimalsBangladeshPublic HealthAnti-Bacterial AgentsAnti-Infective AgentsWater Pollutants, Chemical

Identifiers

PMID40424403
PMCPMC12112158

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.