ArticlePloS one2025
Hematological parameters of newborns from diabetic mothers in Gandhi memorial hospital, Addis Ababa, Ethiopia.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDiabetes mellitus during pregnancy can significantly affect a newborn's hematological profile. However, the hematological profiles among newborns of diabetic mothers and their clinical and prognostic implications are not well explored. Therefore, this study aimed to determine hematological parameters of newborns from diabetic mothers in Gandhi Memorial Hospital, Addis Ababa, Ethiopia, 2024.
methodsA comparative cross-sectional study was carried out at Gandhi Memorial Hospital from March to May 2024. A total of 196 newborns -98 from diabetic mothers and 98 from apparently healthy mothers-were conveniently enrolled in the study. A hematological profile test was assayed using a Sysmex XN-550 analyzer from the whole blood of mothers and cord blood of newborns collected in EDTA. Glucose was measured using a Cobas C311 analyzer from serum collected using SST test tube. Data was entered and analyzed using SPSS version 26, with descriptive statistics, proportions, and independent t-tests. A P-value of less than 0.05 was considered statistically significant.
resultsThe study found that the mean ± SD value of red blood cell count was 4.87 ± 0.68 vs 3.33 ± 0.98 x1012/L (P < 0.001), hemoglobin 17.48 ± 2.69 vs 12.08 ± 3.48 g/dL (P < 0.001), hematocrit 49.83 ± 7.47 vs 36.13 ± 8.97% (P < 0.001), red cell distribution width 18.35 ± 2.68 vs 17.27 ± 1.92% (P < 0.001), platelet distribution width 12.26 ± 1.80 vs 11.69 ± 1.76% (P = 0.028), and platelet large cell ratio was 26.05 ± 5.27 vs 24.07 ± 2.21% (P = 0.001) were significantly higher in newborns born to diabetic mothers compared to controls. Polycythemia was seen in large numbers in newborns born to diabetic mothers (56.1%, 55/98 vs 1%, 1/98). On the other hand, the platelet count and PCT values were significantly lower in newborns from diabetic mothers than controls, with a mean value of 239.69 ± 92.52 (103/µL) and 0.24 ± 0.09 (%), respectively, with a P value < 0.001.
conclusionThe hematological profile shows a significant difference among newborns from mothers with diabetes and apparently healthy mothers. Therefore, it is better to consider hematological parameters as a screening tool for early detection of hematological complications in newborns from diabetic mothers, and this screening should be encouraged.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.