Evidence map›Paper›PMID 40424205›Full record

ArticleAndrology2026

Reliability of suprapubic pedicled phalloplasty to address genital gender-affirming surgery in transgender men: A single-center cohort analysis.

Mattia Anfosso, Lorenzo Cirigliano, Mirko Preto, Paolo Gontero, Marco Falcone

Abstract read
In one paragraph

Article in Andrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mattia AnfossoCenter for Reproductive Medicine and Andrology/Clinical and Surgical Andrology, University Hospital of Münster, Münster, Germany.ORCID 0009-0005-7314-4608
Lorenzo CiriglianoUrology Clinic - A.O.U. "Cittàdella Salute e della Scienza"- Molinette Hospital, University of Turin, Turin, Italy.ORCID 0000-0002-8732-4272
Mirko PretoUrology Clinic - A.O.U. "Cittàdella Salute e della Scienza"- Molinette Hospital, University of Turin, Turin, Italy.ORCID 0000-0002-8144-6498
Paolo GonteroUrology Clinic - A.O.U. "Cittàdella Salute e della Scienza"- Molinette Hospital, University of Turin, Turin, Italy.ORCID 0000-0002-9714-6596
Marco FalconeUrology Clinic - A.O.U. "Cittàdella Salute e della Scienza"- Molinette Hospital, University of Turin, Turin, Italy.ORCID 0000-0003-1101-892X

Funding

Bundesministerium für Bildung und Forschung 01GR2303the German Federal Ministry for Education and Researchthe project ReproTrackMS-Centre for Research and Development of Reproductive Scientists 01GR2303
6 · The paper itself

Abstract

backgroundOver the years, numerous techniques have been used to address genital gender-affirming surgery (GGAS) in transgender men. Among the proposed surgical options to address TPC in transgender men, suprapubic pedicled phalloplasty (SPP) has rarely been considered in the current scientific literature.

objectivesThe aim of the study is to report the surgical outcomes of the first step of suprapubic pedicled phalloplasty (SPP)-with or without urethral lengthening (UL)-evaluating possible risk factors affecting the incidence of complications.

methodsThe study was conducted as a retrospective, single-center analysis at a regional tertiary referral center. Between April 2006 and August 2024, 40 transgender men underwent GGAS at our center. GGAS was conducted as a multistage procedure, consisting of (1) SPP (2) eventual radial artery-based forearm free-flap urethroplasty, (3) glans sculpting, join-up, vaginectomy and scrotoplasty, and (4) penile prosthesis implantation. Surgery time, intra- and postoperative complications, and hospital stay were selected as variables for surgical outcomes.

resultsThe median operative time was 130 min (111-158 min). Partial necrosis of the phallus was detected in 4 cases (10.5%) it was easily managed through a minor outpatient procedure. The median length loss after debridement was 1.3 cm (0.5-2 cm), without significant impact on the final length. A total loss of the neophallus occurred in a single case (2.5%) and required a staged salvage TPC. In the present series, only 14 patients (35%) opted for urethral reconstruction: 8 (20%) required a perineostomy, 4 (10%) underwent radial artery urethroplasty (RAU), while the remaining 5% required an additional metoidioplasty with urethral lengthening, ensuring that the clitoris was not incorporated into the neophallus during penile construction. Univariate and multivariate analyses failed to highlight any possible risk factors influencing the incidence of postoperative complications. The lack of a comparison group or randomization, the limited follow-up, and the absence of patient-reported outcome analysis are the main limitations of our study.

conclusionOur evidence suggests that SPP is a reliable and technically accessible option for GGAS in transgender men, particularly when microsurgery is contraindicated. The technique offers the advantage of accommodating the patient's needs for urethral lengthening, simplifying the surgical process, and reducing operative times. While vascular complications may occur relatively frequently, they are mostly minor and can be managed with simple outpatient procedures.

Indexed as

Gender-Affirming SurgeryPenisAdultHumansMaleMiddle AgedPhalloplastyPostoperative ComplicationsRetrospective StudiesTransgender PersonsTreatment OutcomeUrethraYoung Adultphalloplastytotal phallic construction (TPC)transgender men

Identifiers

PMID40424205
PMCPMC12670471

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.