Evidence map›Paper›PMID 40423748›Full record

ReviewInternational journal of biometeorology2025

Comprehensive review of dermatological and cosmeceutical manifestations of thermal water and future insights.

Shamsa Kanwal, Enass Y Osman, Imen Khiari

Abstract readReview
In one paragraph

Review in International journal of biometeorology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shamsa KanwalDepartment of Medical, Oral and Biotechnological Sciences, University of Chieti - Pescara "G. d'Annunzio", 66100, Chieti, Italy. shamsa.kanwal@unich.it.
Enass Y OsmanDepartment of Pharmacology and Toxicology, Tanta University, Tanta, Egypt.
Imen KhiariGeoresources Laboratory of Water Research and Technologies Center (CERTE), Technopole Borj Cedria, BP273, Soliman, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Balneotherapy is a widely accepted and well-practiced treatment modality for dermatological diseases in many countries worldwide. The use of balneotherapy approaches for skin disease management is continuously increasing, but the mechanism by which thermal water affects the treatment of different dermatological conditions has not been fully explored. This comprehensive review seeks to consolidate scientific findings regarding the effects of thermal water in the treatment of different skin diseases, such as psoriasis, atopic dermatitis, acne, ichthyosis, and lichen planus, as well as its cosmeceutical effects, drawing from both in vitro and in vivo research. This review analyzed both in vitro and in vivo studies to validate the anti-inflammatory, immunomodulatory, and antioxidant potential of thermal water in dermatology. Thermal water exhibits these properties, making it beneficial for treating various skin conditions and enhancing cosmeceutical effects." Many studies have strongly demonstrated the therapeutic benefits of different thermal waters for the successful treatment of many skin diseases, and these materials have been incorporated into cosmetics for skin hydration and anti-aging and anti-wrinkle effects. The physicochemical and microbial characteristics of thermal water contribute to its therapeutic properties, with sulfurous water being particularly effective due to their favorable mineral composition and antioxidative effects.Although the cosmetic properties of thermal water are well described, further research is needed to identify specific mineral and microbial profiles for incorporation into cosmetic products and to integrate advanced technologies and approaches to increase the effectiveness of formulated products. Should aim to clarify the underlying mechanisms of action of thermal waters, investigate optimal treatment protocols, and assess their long-term efficacy. Longitudinal clinical trials are also needed to assess the long-term benefits and safety of these treatments, paving the way for standardized protocols in dermatological care.

Indexed as

BalneologyCosmeceuticalsSkin DiseasesWaterAnimalsAntioxidantsHumansAntioxidantsCosmeceuticalsWaterBalneotherapyCosmetic effectsIn vitroIn vivoSkin diseasesTherapeutic effectsThermal water

Identifiers

PMID40423748
PMCPMC12287192

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.