SynthesisJournal of neural transmission (Vienna, Austria : 1996)2025
Comparison of therapeutic efficacy in depression between repetitive TMS and deep TMS.
Synthesis in Journal of neural transmission (Vienna, Austria : 1996), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Physical Therapy for Treatment-Resistant Depression A Comprehensive Review of Efficacy, Safety, and Evidence Grading.Neuropsychiatric disease and treatment · 2026Review
- Article
- Comparison of rTMS and dTMS in TRD: evidence gaps, cost-effectiveness, and ethical priorities.Frontiers in psychiatry · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Transcranial Magnetic Stimulation (TMS) is a non-invasive neuromodulation technique with promising potential in treating psychiatric and neurological disorders. By offering an alternative to surgery or medication, TMS could significantly enhance patient outcomes and quality of life, particularly for those with conditions resistant to traditional therapies. With ongoing research advancements, TMS may become a cornerstone of personalized medicine, enabling treatments tailored to individual brain patterns and needs. Although rTMS has FDA approval and dTMS has clearance for treating treatment-resistant depression (TRD), comparative studies between these techniques remain scarce. This systematic review aims to assess and compare the efficacy of rTMS and dTMS in TRD through the analysis of observational studies and clinical trials that directly compare these two treatments. Relevant literature was identified through searches in Web of Science, Scopus, Cochrane Library, PsycINFO, PubMed, and Open Gray, covering studies published in English from 2014 to 2024. Only three studies, including one observational study and two RCTs, met inclusion criteria, indicating similar efficacy and safety for both techniques. This review highlights that both rTMS and dTMS are effective and safe for treating TRD, with no significant differences in symptom remission. However, dTMS is significantly more expensive, making rTMS a more viable option in resource-limited settings. The review underscores the need for further multicenter and long-term studies to better clarify the cost-effectiveness of these treatments.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.