Evidence map›Paper›PMID 40423569›Full record

ArticleFacts, views & vision in ObGyn2025

Feasibility of single step hysteroscopic myomectomy: fibroid size is the most significant factor based on data from a single centre and surgeon.

Ursula Catena, Eleonora La Fera, Diana Giannarelli, Andrea Scalera, Emma Bonetti, Federica Bernardini, Federica Campolo, Francesco Fanfani, Giovanni Scambia

Abstract read
In one paragraph

Article in Facts, views & vision in ObGyn, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ursula CatenaUnit of Gynecologic Oncology, Department for Women's and Children's Health and Public Health, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.ORCID 0000-0002-7813-7993
Eleonora La FeraUnit of Gynecologic Oncology, Department for Women's and Children's Health and Public Health, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.ORCID 0000-0002-2572-0886
Diana GiannarelliBiostatistics Unit, Scientific Directorate, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.ORCID 0000-0002-6085-1195
Andrea ScaleraDepartment of Women's, Children's, General and Specialist Surgery, University of Campania "Luigi Vanvitelli", Naples, Italy.ORCID 0009-0007-2265-7096
Emma BonettiDepartment of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.ORCID 0009-0005-0836-5260
Federica BernardiniUnit of Gynecologic Oncology, Department for Women's and Children's Health and Public Health, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.ORCID 0000-0002-8976-1708
Federica CampoloUnit of Gynecologic Oncology, Department for Women's and Children's Health and Public Health, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.ORCID 0000-0003-3962-3064
Francesco FanfaniUnit of Gynecologic Oncology, Department for Women's and Children's Health and Public Health, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.ORCID 0000-0003-1991-7284
Giovanni ScambiaUnit of Gynecologic Oncology, Department for Women's and Children's Health and Public Health, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.ORCID 0000-0002-9503-9041

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Uterine fibroids are the most common benign solid neoplasms of the uterus. Hysteroscopy represents the gold standard treatment for submucosal fibroids. Objectives: The aim of this study was to retrospectively analyse all consecutive symptomatic patients diagnosed with the International Federation of Gynecology and Obstetrics G0-G3 fibroids who underwent hysteroscopic myomectomy, to identify factors that may influence the feasibility of single step myomectomy. Methods: The study included all consecutive symptomatic patients, diagnosed with G0-G3 fibroid. Surgical procedure was performed by a single experienced surgeon. All patients underwent postoperative hysteroscopic control 30-40 days after the procedure. Main Outcomes Measures: Evaluation of feasibility of hysteroscopic myomectomy in a single surgical step. Results: One hundred and twenty-five patients were included. In 97 women (77.6%) the fibroid was removed in one single step; 28 patients (22.4%) had a residual fibroid. Of these patients, in 10 cases (35.7%) the residual fibroid was removed during the office hysteroscopic control, 16 (57.2%) and 2 (7.1%) patients required II- and III-time myomectomy, respectively. 85.6% of patients did not need a second time surgery under general anaesthesia. At univariate and multivariate analysis, diameter was found to be the parameter most related to single-step fibroid removal with Conclusions: In expert hands, single step hysteroscopic myomectomy is feasible for G0-3 fibroids. The possibility to use miniaturized instruments for myomectomy may improve the surgical outcomes and prevent intra- and post-operative complications, in particular uterine perforation by avoiding cervical dilation. Further studies are needed to evaluate the true efficacy of 15 Fr mini-resectoscope in the removal of G0-G3 fibroids <3 cm. What is New?: Hysteroscopic myomectomy in a single surgical step is feasible for G0-G3 fibroids, with diameter being the only independent factor influencing the success of the procedure. In expert hands, the success rate of single step myomectomy by using miniaturized instruments in fibroids ≤3 cm, is 89.4%.

Indexed as

Fibroidhysteroscopymyomamyomectomy

Identifiers

PMID40423569
PMCPMC12233117

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.