Evidence map›Paper›PMID 40423467›Full record

ReviewToxics2025

Micro- and Nanoplastics and Fetal Health: Challenges in Assessment and Evidence from Epidemiological Studies.

Ankica Sekovanić, Tatjana Orct, Zorana Kljaković-Gašpić

Abstract readReview
In one paragraph

Review in Toxics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Micro and Nanoplastics and Obstetric Outcomes in Humans and Animals: A Systematic Review.International journal of environmental research and public health · 2026
    Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ankica SekovanićDivision of Occupational and Environmental Health, Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.ORCID 0000-0001-6855-1018
Tatjana OrctDivision of Occupational and Environmental Health, Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.ORCID 0000-0002-9301-4035
Zorana Kljaković-GašpićDivision of Occupational and Environmental Health, Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.ORCID 0000-0002-0439-2131

Funding

Croatian Science Foundation HrZZ-IP-2024-05-8815European Regional Development Fund KK.01.1.1.02.0007European Union - Next Generation EU Program Contract of 8 December 2023, Class: 643-02/23-01/00016, Reg. no. 533-03-23-0006
6 · The paper itself

Abstract

The usage of plastics in life and industrial applications has led to global environmental pollution by micro- and nanoplastics (MPs/NPs). Despite their widespread occurrence in the environment, little is known about their presence in humans and the potential implications for human health, particularly maternal and fetal health during the prenatal and neonatal periods. Studies on experimental animals indicate that exposure to MPs/NPs can lead to neurological abnormalities in offspring and hemodynamic alterations in the placenta and fetal cerebral arteries. These findings underscore the need for further epidemiological studies that examine the effects of MPs/NPs on fetal health during pregnancy, a critical period for neurological development. This review summarizes the existing knowledge on the effects of prenatal exposure to MPs/NPs on fetal development and birth outcomes in humans and provides a detailed overview of the challenges encountered in contamination prevention, quality assurance and quality control in analytical procedures. It also discusses the sampling and digestion methods used for the extraction of MPs/NPs from biological samples of maternal and fetal origin, highlighting the difficulties associated with accurately quantifying these particles in complex biological matrices, identifying the gaps in current research, and suggesting recommendations to improve methodologies for assessing the risks associated with prenatal MP/NP exposure.

Indexed as

birth outcomesdigestion and extractionmicroplasticsnanoplasticsparticlespollutionprenatal exposure

Identifiers

PMID40423467
PMCPMC12115451

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.