Evidence map›Paper›PMID 40423454›Full record

ArticleToxics2025

Impact of Pesticide Exposure on High-Frequency Auditory Thresholds and Cochlear Function in Young People Residing near Agricultural Areas.

Felipe Munoz, Cristian Aedo-Sanchez, Felipe Paredes-Aravena, Enzo Aguilar-Vidal, Pedro Jilberto-Vergara, Gonzalo Terreros

Abstract read
In one paragraph

Article in Toxics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Felipe MunozLaboratorio de Neurociencia Sensorial Perceptual y Cognitiva, Instituto de Ciencias de la Salud, Universidad de O'Higgins, Rancagua 2820000, Chile.ORCID 0009-0003-2102-5530
Cristian Aedo-SanchezDepartamento de Tecnología Médica, Facultad de Medicina, Universidad de Chile, Santiago 8380453, Chile.ORCID 0000-0003-0670-7843
Felipe Paredes-AravenaEscuela de Salud, Universidad de O'Higgins, Rancagua 2820000, Chile.
Enzo Aguilar-VidalDepartamento de Tecnología Médica, Facultad de Medicina, Universidad de Chile, Santiago 8380453, Chile.ORCID 0000-0002-1768-6171
Pedro Jilberto-VergaraLaboratorio de Neurociencia Sensorial Perceptual y Cognitiva, Instituto de Ciencias de la Salud, Universidad de O'Higgins, Rancagua 2820000, Chile.ORCID 0009-0001-1447-2434
Gonzalo TerrerosLaboratorio de Neurociencia Sensorial Perceptual y Cognitiva, Instituto de Ciencias de la Salud, Universidad de O'Higgins, Rancagua 2820000, Chile.ORCID 0000-0002-0227-7578

Funding

ANID FONDECYT INICIACION 11200881
6 · The paper itself

Abstract

Pesticide exposure poses a significant health risk, with emerging evidence suggesting its impact on auditory function. This study investigated the effects of pesticide exposure on hearing in young rural residents living near agricultural areas in Chile's O'Higgins Region. We evaluated 51 participants (31 exposed, 20 unexposed) aged 18-35 years, using comprehensive audiological assessments including high-frequency audiometry, distortion product otoacoustic emissions (DPOAEs), and auditory brainstem responses (ABR). Participants were classified based on residential proximity to agricultural areas, with exposed individuals living around 400 m or less from monoculture fields. Results revealed significant differences in high-frequency hearing thresholds (14 and 16 kHz) in exposed individuals. The exposed group showed a higher number of absent DPOAEs and reduced ABR wave V amplitude in the right ear compared to the unexposed group. Additionally, the wave V/I ratio was significantly lower in exposed individuals. These findings suggest that pesticide exposure, even without direct occupational contact, may induce measurable changes in auditory function, particularly affecting high-frequency hearing and neural responses. These results emphasize the need for enhanced monitoring and protective measures for populations residing near agricultural areas where pesticides are extensively used.

Indexed as

auditory brainstem responsedistortion product otoacoustic emissionshearing lossototoxicitypesticides

Identifiers

PMID40423454
PMCPMC12115959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.