Characteristics of Neonicotinoids in Colostrum from Shanghai, China (2007-2019): Concentration Levels, Temporal Trends, and Potential Health Risk.

Kexin Li, Minghui Fu, Bingli Lei, Xiuhua Shen, Xinyu Zhang, Jun Xu, Xiaolan Zhang

Abstract read

In one paragraph

Article in Toxics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed

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1 · What the graph read from it

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1 citing paper in PubMed.

Urinary Biomonitoring and Risk Prioritization of Traditional and Emerging Neonicotinoids in School-Aged Children, South China.Toxics · 2026
Article

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5 · Who and what money

Authors and funding

7 authors.

Kexin LiSchool of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China.

Minghui FuSchool of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China.

Bingli LeiSchool of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China.

Xiuhua ShenSchool of Public Health, Hongqiao International Institute of Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.ORCID 0000-0001-8734-5041

Xinyu ZhangDepartment of Clinical Nutrition, College of Health Science and Technology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.ORCID 0000-0003-3472-8393

Jun XuShanghai Second People's Hospital, Shanghai 200011, China.

Xiaolan ZhangSchool of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China.

Funding

Key Laboratory of Milk and Dairy Products Detection and Monitoring Technology, State Administration for Market Regulation MDPDMT-2022-02The presented study was supported by the Key Discipline Project of the Three Year Action Plan (2023-2025) for Public Health System Construction in Shanghai GWVI-11.1-41

6 · The paper itself

Abstract

Neonicotinoids (NEOs) are widely used neuroactive insecticides with several adverse effects on human health. This study examined 186 colostrum samples collected at three time points between 2007 and 2019 from Shanghai, China to investigate the distribution and temporal variations of NEOs. The median total concentration (ΣNEOs) was 136 ng/L, with the imidacloprid equivalent concentration (IMIeq) of 249 ng/L. N-desmethyl-acetamiprid (DM-ACE) had the highest median level at 49.6 ng/L, accounting for 43.9% of ΣNEOs, followed by imidacloprid (IMI) (20.1 ng/L and 22.1%). Thiamethoxam (THM), clothianidin, and acetamiprid were also identified as important parent compounds (p-NEOs). Temporal variations suggested a decrease in ΣNEOs, IMIeq, and DM-ACE concentrations from 2013 to 2019; however, the total concentrations of p-NEOs remained comparable. Distinct trends were also observed in the concentrations of dinotefuran and IMI. Maternal body mass index and weight changes, which reflect the dietary habits of mothers, appeared to influence IMI and THM levels. No statistically significant relationships were found between colostrum concentrations and birth parameters using full-term birth data in 2019. The estimated hazard quotients (≤0.003), which were far below the risk threshold of 1, generally indicated negligible health risks for breastfeeding neonates. Nevertheless, the substantial contribution from several p-NEOs warrants further investigation.

Indexed as

colostrumhealth risk assessmentneonicotinoidstemporal variation

Identifiers

PMID40423445

DOI10.3390/toxics13050366

PMCPMC12115666

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