Evidence map›Paper›PMID 40423360›Full record

ArticleTropical medicine and infectious disease2025

Prognostic Value of the Brixia Radiological Score in COVID-19 Patients: A Retrospective Study from Romania.

George-Cosmin Popovici, Costinela-Valerica Georgescu, Alina Condratovici Plesea, Anca-Adriana Arbune, Gutu Cristian, Manuela Arbune

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Article in Tropical medicine and infectious disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

6 authors.

George-Cosmin PopoviciSchool for Doctoral Studies in Biomedical Sciences, "Dunarea de Jos" University from Galati, 800008 Galati, Romania.
Costinela-Valerica GeorgescuPharmaceutical Sciences Department, "Dunarea de Jos" University from Galati, 800008 Galati, Romania.
Alina Condratovici PleseaMedical Department, "Dunarea de Jos" University from Galati, 800008 Galati, Romania.ORCID 0000-0002-2710-7284
Anca-Adriana ArbuneNeurology Department Clinic Institute Fundeni Bucharest, 022328 Bucharest, Romania.ORCID 0000-0002-9500-4498
Gutu Cristian"Dr. Aristide Serfioti" Military Emergency Hospital, 800008 Galati, Romania.ORCID 0009-0000-5081-3577
Manuela ArbuneMedical Clinic Department, "Dunarea de Jos" University from Galati, 800008 Galati, Romania.ORCID 0000-0002-4762-0755

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The novel coronavirus pandemic, SARS-CoV-2, has a variable clinical spectrum, ranging from asymptomatic to critical forms. High mortality and morbidity rates have been associated with risk factors such as comorbidities, age, sex, and virulence factors specific to viral variants. Material and Methods: We retrospectively evaluated imaging characteristics using the Brixia radiological score in relation to favorable or unfavorable outcomes in adult patients. We included COVID-19 cases, admitted between 2020 and 2022, in a specialized pulmonology hospital with no intensive care unit. We analyzed 380 virologically confirmed COVID-19 cases, with a mean age of 52.8 ± 13.02 years. The mean Brixia radiological score at admission was 5.13 ± 3.56, reflecting predominantly mild-to-moderate pulmonary involvement. Multivariate analysis highlighted the utility of this score as a predictive marker for COVID-19 prognosis, with values >5 correlating with other severity biomarkers, NEWS-2 scores, and a lack of vaccination and hospitalization delay of more than 6 days from symptom onset. Summarizing, the Brixia score is itself an effective tool for screening COVID-19 cases at risk of death for early recognition of clinical deterioration and for decisions regarding appropriate care settings. Promoting vaccination can reduce the severity of radiological lesions, thereby decreasing the risk of death. Technologies based on artificial intelligence could optimize diagnosis and management decisions.

Indexed as

Brixia scoreCOVID-19emerging infectious diseasepredictor death

Identifiers

PMID40423360
PMCPMC12115630

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.