Evidence map›Paper›PMID 40423354›Full record

ArticleTropical medicine and infectious disease2025

Factors Associated with Prolonged Mechanical Ventilation and 30-Day Mortality in Intubated COVID-19 Patients with Invasive Fungal Infections: A Retrospective Observational Study.

Hung Manh Than, Thang Van Dao, Truong Van Cao, Tuyen Van Duong, Thach Ngoc Pham, Cap Trung Nguyen, Phu Dinh Vu, Nam Van Le, Binh Nhu Do, Phuong Viet Nguyen and 2 more

Abstract read
In one paragraph

Article in Tropical medicine and infectious disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hung Manh ThanEmergency Department, National Hospital for Tropical Diseases, Hanoi 11519, Vietnam.ORCID 0000-0002-3227-6947
Thang Van DaoInternational Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan.ORCID 0000-0002-4973-0472
Truong Van CaoTraining and Direction Center, Institute of Military Preventive Medicine, Hanoi 11519, Vietnam.
Tuyen Van DuongInternational Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan.ORCID 0000-0002-2287-0723
Thach Ngoc PhamDirector Office, National Hospital for Tropical Diseases, Hanoi 11519, Vietnam.
Cap Trung NguyenDirector Office, National Hospital for Tropical Diseases, Hanoi 11519, Vietnam.
Phu Dinh VuIntensive Care Unit, National Hospital for Tropical Diseases, Hanoi 11519, Vietnam.
Nam Van LeDepartment of Infectious Diseases, Military Hospital 103, Vietnam Military Medical University, Hanoi 12108, Vietnam.
Binh Nhu DoDepartment of Infectious Diseases, Military Hospital 103, Vietnam Military Medical University, Hanoi 12108, Vietnam.ORCID 0000-0002-1377-3921
Phuong Viet NguyenDepartment of Infectious Diseases, Military Hospital 103, Vietnam Military Medical University, Hanoi 12108, Vietnam.
Ha Nhi VuDepartment of Microbiology, Faculty of Basic Medicine, Thai Nguyen University of Medicine and Pharmacy, Thai Nguyen 24117, Vietnam.
Duong Minh VuIntensive Care Unit, Military Hospital 103, Vietnam Military Medical University, Hanoi 12108, Vietnam.ORCID 0009-0002-6037-3848

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID-19-associated invasive fungal infections (CAIFIs) contribute to increased mortality and morbidity rates. This study explores the epidemiology, laboratory parameters, radiological characteristics, treatments, and 30-day mortality risks of CAIFI in critically ill intubated patients while also evaluating factors associated with prolonged mechanical ventilation (PMV) in this population. Adults admitted to a tertiary hospital from 1 April 2021 to 31 March 2022 who were diagnosed with severe COVID-19, required invasive mechanical ventilation, and developed invasive fungal infection (IFI) during hospitalization were analyzed in this retrospective cohort study. Among 150 patients, 65 (43.3%) required PMV, with an in-hospital mortality rate of 64%.

Indexed as

associated factorsCOVID-19invasive fungal infectionmortality riskprolonged mechanical ventilation

Identifiers

PMID40423354
PMCPMC12115372

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.