Evidence map›Paper›PMID 40423332›Full record

ArticleToxins2025

Ustilaginoidin D Induces Acute Toxicity and Hepatotoxicity in Mice.

Bo Wang, Xiaolong Bai, Min Zhang, Xiangxiang Liu, Muhammad Zulqar Nain Dara, Lingjing Liu, Mingming Ou, Dayong Li, Jiyang Wang, Ling Liu and 1 more

Abstract read
In one paragraph

Article in Toxins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Journal of fungi (Basel, Switzerland) · 2026
    Article
  4. Comparative genomics of Eastern-IndianFrontiers in fungal biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Bo WangCollege of Plant Protection, Jilin Provincial Key Laboratory of Green Management of Crop Pests and Diseases, Jilin Agricultural University, Changchun 130118, China.ORCID 0000-0001-9665-5973
Xiaolong BaiCollege of Plant Protection, Jilin Provincial Key Laboratory of Green Management of Crop Pests and Diseases, Jilin Agricultural University, Changchun 130118, China.
Min ZhangCollege of Plant Protection, Jilin Provincial Key Laboratory of Green Management of Crop Pests and Diseases, Jilin Agricultural University, Changchun 130118, China.
Xiangxiang LiuCollege of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.
Muhammad Zulqar Nain DaraCollege of Plant Protection, Jilin Provincial Key Laboratory of Green Management of Crop Pests and Diseases, Jilin Agricultural University, Changchun 130118, China.ORCID 0000-0002-9980-2999
Lingjing LiuCollege of Plant Protection, Jilin Provincial Key Laboratory of Green Management of Crop Pests and Diseases, Jilin Agricultural University, Changchun 130118, China.
Mingming OuCollege of Plant Protection, Jilin Provincial Key Laboratory of Green Management of Crop Pests and Diseases, Jilin Agricultural University, Changchun 130118, China.
Dayong LiCollege of Plant Protection, Jilin Provincial Key Laboratory of Green Management of Crop Pests and Diseases, Jilin Agricultural University, Changchun 130118, China.
Jiyang WangCollege of Plant Protection and the Ministry of Agriculture Key Laboratory of Pest Monitoring and Green Management, China Agricultural University, Beijing 100193, China.ORCID 0000-0003-4781-3829
Ling LiuCollege of Plant Protection, Jilin Provincial Key Laboratory of Green Management of Crop Pests and Diseases, Jilin Agricultural University, Changchun 130118, China.ORCID 0000-0001-8668-4842
Wenxian SunCollege of Plant Protection, Jilin Provincial Key Laboratory of Green Management of Crop Pests and Diseases, Jilin Agricultural University, Changchun 130118, China.

Funding

Jilin Province Natural Science Foundation Project (20230101253JC) 111 project B13006
6 · The paper itself

Abstract

Ustilaginoidin D is a type of bis-naphtho-γ-pyrone mycotoxin produced by Ustilaginoidea virens, the causal agent of rice false smut. Although previous studies have demonstrated the inhibitory effect of ustilaginoidin D on ATP synthesis and cancer cell growth in mice, its specific health risks remain unclear. Here, we reveal that ustilaginoidin D is highly toxic to mice with an LD

Indexed as

Chemical and Drug Induced Liver InjuryLiverMycotoxinsPyronesAlanine TransaminaseAnimalsMaleMiceAlanine TransaminaseMycotoxinsPyroneshepatotoxicityhuman healthmicerice false smutustilaginoidin D

Identifiers

PMID40423332
PMCPMC12115440

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.