Evidence map›Paper›PMID 40423145›Full record

ArticleNanomaterials (Basel, Switzerland)2025

Gold Nanocages with a Long Surface Plasmon Resonance Peak Wavelength as Contrast Agents for Optical Coherence Tomography Imaging at 1060 nm.

Yongping Chen, Jiefeng Xi, Vinh Nguyen Du Le, Jessica Ramella-Roman, Xingde Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Yongping ChenDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21205, USA.
Jiefeng XiDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21205, USA.
Vinh Nguyen Du LeBiomedical Engineering Department, Florida International University, Miami, FL 33174, USA.ORCID 0000-0002-4054-4200
Jessica Ramella-RomanBiomedical Engineering Department, Florida International University, Miami, FL 33174, USA.ORCID 0000-0002-5710-6004
Xingde LiDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21205, USA.ORCID 0000-0002-4725-3297

Funding

A New Integrated Endoscope SystemR01EB007636 · NIBIB · UNIVERSITY OF WASHINGTON · PI LIN, LIH Y · 2009 to 2012
$2.3M
Molecular Contrast Agents Based on Gold Nanocages for OCT Imaging of CancerR01CA120480 · NCI · UNIVERSITY OF WASHINGTON · PI LI, XINGDE · 2006 to 2009
$1.1M
NCI NIH HHS R01 CA120480NIBIB NIH HHS R01 EB007636the National Institutes of Health (NIH) and the National Science Foundation (NSF) (R01 CA120480 and 1R01 EB007636) (IIP-0724231).
6 · The paper itself

Abstract

There is growing interest in optical coherence tomography (OCT) imaging at a wavelength of 1060 nm. However, potential contrast agents for OCT imaging at this specific wavelength has not been thoroughly investigated. In this study, we present the synthesis and optical characterization of gold nanocages with a small edge length (~65 nm) and a surface plasmon resonance peak around 1060 nm. These nanocages represent a class of potential contrast agents for OCT at 1060 nm. OCT imaging experiments were conducted on phantoms and in vivo mouse tissues using a 1060 nm swept-source OCT system, demonstrating significant enhancement in imaging contrast due to the presence of the gold nanocages.

Indexed as

biomedical imagingcontrast agentgold nanocageoptical coherence tomography (OCT)

Identifiers

PMID40423145
PMCPMC12113713

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.