Evidence map›Paper›PMID 40423129›Full record

ArticleNanomaterials (Basel, Switzerland)2025

Magnetic Bifunctional Ru-Enzyme Catalyst Allows for Sustainable Conversion of Cellulose Derivative to D-Sorbitol.

Boris B Tikhonov, Daniil R Lisichkin, Alexandrina M Sulman, Alexander I Sidorov, Alexey V Bykov, Yury V Lugovoy, Alexey Y Karpenkov, Lyudmila M Bronstein, Valentina G Matveeva

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Biomass valorization using 3D-printed catalysts.Communications chemistry · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Boris B TikhonovDepartment of Biotechnology, Chemistry and Standardization, Tver State Technical University, 22 A. Nikitina Str., 170026 Tver, Russia.ORCID 0000-0002-6977-1730
Daniil R LisichkinDepartment of Biotechnology, Chemistry and Standardization, Tver State Technical University, 22 A. Nikitina Str., 170026 Tver, Russia.ORCID 0009-0008-7865-2451
Alexandrina M SulmanDepartment of Biotechnology, Chemistry and Standardization, Tver State Technical University, 22 A. Nikitina Str., 170026 Tver, Russia.
Alexander I SidorovDepartment of Biotechnology, Chemistry and Standardization, Tver State Technical University, 22 A. Nikitina Str., 170026 Tver, Russia.
Alexey V BykovDepartment of Biotechnology, Chemistry and Standardization, Tver State Technical University, 22 A. Nikitina Str., 170026 Tver, Russia.ORCID 0000-0003-4717-7746
Yury V LugovoyDepartment of Biotechnology, Chemistry and Standardization, Tver State Technical University, 22 A. Nikitina Str., 170026 Tver, Russia.
Alexey Y KarpenkovDepartment of Condensed Matter Physics, Tver State University, Zhelyabova St. 33, 170100 Tver, Russia.
Lyudmila M BronsteinDepartment of Biotechnology, Chemistry and Standardization, Tver State Technical University, 22 A. Nikitina Str., 170026 Tver, Russia.ORCID 0000-0002-0438-8132
Valentina G MatveevaDepartment of Biotechnology, Chemistry and Standardization, Tver State Technical University, 22 A. Nikitina Str., 170026 Tver, Russia.ORCID 0000-0002-3291-4865

Funding

Russian Science Foundation 24-79-10042
6 · The paper itself

Abstract

Here, we report the development of a novel bifunctional nanobiocatalyst for a one-pot cascade transformation of carboxymethyl cellulose (CMC) to D-sorbitol. The nanobiocatalyst is based on magnetic nanoparticle aggregates (MNAs) functionalized with chitosan (CS) cross-linked by tripolyphosphate (TPP). It contains two types of catalytic sites: cellulase (Cel, 5 wt.%) and Ru (3 wt.%) nanoparticles (NPs) of 0.7 nm in diameter. To optimize the nanobiocatalyst structure and composition, we first synthesized the biocatalyst, MNA-CSP-Cel (CSP stands for the CS layer cross-linked by TPP), as well as the nanocatalyst, MNA-CSP-Ru, and studied them in the one-step reactions of hydrolysis and hydrogenation, respectively. The data obtained allowed us to optimize the composition and properties of the bifunctional nanobiocatalyst, MNA-CSP-Ru-Cel, and to choose the best reaction conditions for the cascade process. MNA-CSP-Ru-Cel was characterized using transmission electron microscopy (TEM), high-resolution TEM, energy-dispersive spectroscopy, X-ray diffraction, X-ray photoelectron spectroscopy, and porosity measurements. The knowledge obtained enabled us to perform a cascade transformation of CMC to D-sorbitol with a yield of 83.2% for 10 h at 70 °C and a hydrogen pressure of 4 MPa. The yield demonstrated in this work is much higher than that reported to date for the same cascade process.

Indexed as

cascade processcellulasemagnetitenanobiocatalystnanoparticleRu

Identifiers

PMID40423129
PMCPMC12114484

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.