Evidence map›Paper›PMID 40423067›Full record

ArticleJournal of personalized medicine2025

Yeast-Produced Human Recombinant Lysosomal β-Hexosaminidase Efficiently Rescues GM2 Ganglioside Accumulation in Tay-Sachs Disease.

Orhan Kerim Inci, Andrés Felipe Leal, Nurselin Ates, Diego A Súarez, Angela Johana Espejo-Mojica, Carlos Javier Alméciga-Diaz, Volkan Seyrantepe

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of personalized medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Orhan Kerim InciIzmir Institute of Technology, Department of Molecular Biology and Genetics, Gulbahce Campus, Urla, Izmir 35430, Turkey.ORCID 0000-0003-0680-8425
Andrés Felipe LealInstitute for the Study of Inborn Errors of Metabolism, Faculty of Sciences, Pontificia Universidad Javeriana, Bogotá 110231, Colombia.ORCID 0000-0001-5956-1986
Nurselin AtesIzmir Institute of Technology, Department of Molecular Biology and Genetics, Gulbahce Campus, Urla, Izmir 35430, Turkey.ORCID 0000-0003-4152-3695
Diego A SúarezInstitute for the Study of Inborn Errors of Metabolism, Faculty of Sciences, Pontificia Universidad Javeriana, Bogotá 110231, Colombia.ORCID 0000-0001-9519-4706
Angela Johana Espejo-MojicaInstitute for the Study of Inborn Errors of Metabolism, Faculty of Sciences, Pontificia Universidad Javeriana, Bogotá 110231, Colombia.ORCID 0000-0001-9670-6435
Carlos Javier Alméciga-DiazInstitute for the Study of Inborn Errors of Metabolism, Faculty of Sciences, Pontificia Universidad Javeriana, Bogotá 110231, Colombia.ORCID 0000-0001-6484-1173
Volkan SeyrantepeIzmir Institute of Technology, Department of Molecular Biology and Genetics, Gulbahce Campus, Urla, Izmir 35430, Turkey.ORCID 0000-0002-0243-5011

Funding

Ministerio de Ciencia, Tecnología e Innovación ID 9630/CT-499-2021Pontificia Universidad Javeriana InvestigarPUJ 20567 and 20646TUBITAK 121N825
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

GM2murine modelP. pastorisrhHex-ATay–Sachs

Identifiers

PMID40423067
PMCPMC12113087

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.