Evidence map›Paper›PMID 40422945›Full record

ArticleJournal of cardiovascular development and disease2025

V

Antonio Pagliaro, Luna Cavigli, Roberta Molle, Elisabetta Iardino, Francesca Anselmi, Francesca Righini, Luca Martini, Valerio Zacà, Giulia Elena Mandoli, Maria Concetta Pastore and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cardiovascular development and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Antonio PagliaroDivision of Cardiology, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.ORCID 0009-0006-8294-3425
Luna CavigliDivision of Cardiology, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.ORCID 0000-0003-3305-792X
Roberta MolleDivision of Cardiology, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.ORCID 0009-0004-4546-6063
Elisabetta IardinoDivision of Cardiology, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.
Francesca AnselmiDivision of Cardiology, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.
Francesca RighiniDivision of Cardiology, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.
Luca MartiniDivision of Cardiology, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.
Valerio ZacàDivision of Cardiology, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.
Giulia Elena MandoliDivision of Cardiology, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.
Maria Concetta PastoreDivision of Cardiology, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.ORCID 0000-0002-7223-141X
Marta FocardiDivision of Cardiology, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.ORCID 0000-0002-0879-8526
Matteo CameliDivision of Cardiology, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.ORCID 0000-0003-3872-8964
Sonia BernazzaliDepartment of Cardiac Surgery, University of Siena, 53100 Siena, Italy.ORCID 0000-0003-1299-3380
Massimo MaccheriniDepartment of Cardiac Surgery, University of Siena, 53100 Siena, Italy.
Marco ChiostriSOD Fisiopatologia Respiratoria, Dipartimento delle Specialistiche Mediche, Az. USL Toscana Centro, 50137 Firenze, Italy.
Flavio D'AscenziDivision of Cardiology, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.ORCID 0000-0002-0947-6836
Serafina ValenteDivision of Cardiology, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accurate prognostic stratification in patients with chronic heart failure and reduced ejection fraction (HFrEF) remains a significant clinical challenge. Many different parameters, including left ventricular (LV) and right ventricular (RV) function and cardiopulmonary exercise testing (CPET) parameters, are available in the literature. LV ejection fraction (LVEF) is the most used parameter in clinical practice. This study aimed to analyze CPET and echocardiographic data in patients under evaluation for heart transplantation (HTx) to identify the parameter that best correlates with cardiac events. Methods and Results. Echocardiography and CPET were performed in patients with HFrEF under evaluation for HTx. The population comprised 170 patients (mean age: 55 ± 9 years; 88% male; non-ischemic etiology: 63%). LVEF was 30.4 ± 7.6%, peak oxygen uptake (Vo

Indexed as

cardiac remodelingcardiopulmonary exercise testingheart failureheart transplantationleft ventricular ejection fractionprognostic stratification

Identifiers

PMID40422945
PMCPMC12112257

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.