Evidence map›Paper›PMID 40422867›Full record

ArticleMetabolites2025

Alcohol Exposure May Increase Prenatal Choline Needs Through Redirection of Choline into Lipid Synthesis Rather than Methyl Donation.

Hannah G Petry, Nipun Saini, Susan M Smith, Sandra M Mooney

Abstract read
In one paragraph

Article in Metabolites, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hannah G PetryDepartment of Nutrition, University of North Carolina, Chapel Hill, NC 27599, USA.ORCID 0009-0007-5187-7792
Nipun SainiDepartment of Nutrition, University of North Carolina, Chapel Hill, NC 27599, USA.ORCID 0000-0001-6775-3486
Susan M SmithDepartment of Nutrition, University of North Carolina, Chapel Hill, NC 27599, USA.ORCID 0000-0003-4782-6857
Sandra M MooneyDepartment of Nutrition, University of North Carolina, Chapel Hill, NC 27599, USA.ORCID 0000-0002-7387-2518

Funding

Craniofacial Morphogenesis in Prenatal Alcohol ExposureR01AA011085 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SMITH, SUSAN M. · 2001 to 2025
$6.3M
Craniofacial Morphogenesis in Prenatal Alcohol ExposureR37AA011085 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SMITH, SUSAN M. · 2007 to 2016
$3.3M
Choline-Related Polymorphisms in Fetal Alcohol Spectrum DisordersR01AA031262 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Sandra M Mooney, SUSAN M. SMITH · 2024 to 2026
$1.4M
Maternal Fetal Metabolic Disruption in Prenatal Alcohol ExposureR00AA028291 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Nipun Saini · 2024 to 2026
$710k
Choline Polymorphisms in FASDUH2AA029056 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SMITH, SUSAN M. · 2021 to 2022
$385k
Maternal Fetal Metabolic Disruption in Prenatal Alcohol ExposureK99AA028291 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SAINI, NIPUN · 2021 to 2022
$275k
Modeling alcohol exposure in gestation and adolescenceR03AA031378 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MOONEY, SANDRA M, ROBINSON, DONITA L · 2024 to 2025
$156k
CRANIOFACIAL MORPHOGENESIS IN PRENATAL ALCOHOL EXPOSURER29AA011085 · NIAAA · UNIVERSITY OF WISCONSIN MADISON · PI SMITH, SUSAN M. · 1996 to 2000
$100k
NIAAA NIH HHS K99 AA028291NIAAA NIH HHS R00 AA028291NIAAA NIH HHS R01 AA011085NIAAA NIH HHS R01 AA031262NIAAA NIH HHS R03 AA031378NIAAA NIH HHS R29 AA011085NIAAA NIH HHS R37 AA011085NIAAA NIH HHS UH2 AA029056NIH HHS AA011085NIH HHS AA02498NIH HHS AA028291NIH HHS AA031262NIH HHS AA031378
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

fetal alcohol spectrum disorderKennedy pathwaymetabolomemouseone carbon metabolismprenatal alcohol

Identifiers

PMID40422867
PMCPMC12113322

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.