Evidence map›Paper›PMID 40422789›Full record

SynthesisMarine drugs2025

Dental Resin Composites Modified with Chitosan: A Systematic Review.

Wojciech Dobrzyński, Paweł J Piszko, Jan Kiryk, Sylwia Kiryk, Mateusz Michalak, Agnieszka Kotela, Julia Kensy, Witold Świenc, Natalia Grychowska, Jacek Matys and 1 more

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Marine drugs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  20. Frontiers in dental medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Wojciech DobrzyńskiDepartment of Dentofacial Orthopedics and Orthodontics, Division of Facial Abnormalities, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, Poland.ORCID 0000-0002-6400-3660
Paweł J PiszkoDepartment of Biomedical Engineering, Faculty of Fundamental Problems of Technology, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland.ORCID 0000-0002-7577-8509
Jan KirykDental Surgery Department, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, Poland.ORCID 0000-0002-5442-1412
Sylwia KirykDepartment of Pediatric Dentistry and Preclinical Dentistry, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, Poland.ORCID 0000-0001-9062-4156
Mateusz MichalakMedical Center of Innovation, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, Poland.
Agnieszka KotelaMedical Center of Innovation, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, Poland.ORCID 0009-0008-4353-4607
Julia KensyFaculty of Dentistry, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, Poland.ORCID 0009-0008-1680-793X
Witold ŚwiencMedical Center of Innovation, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, Poland.ORCID 0000-0003-4292-1572
Natalia GrychowskaDepartment of Dental Prosthetics, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, Poland.ORCID 0000-0002-1024-9489
Jacek MatysDental Surgery Department, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, Poland.ORCID 0000-0002-3801-0218
Maciej DobrzyńskiDepartment of Pediatric Dentistry and Preclinical Dentistry, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, Poland.ORCID 0000-0003-2368-1534

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis systematic review aims to evaluate the impact of incorporating chitosan into dental resin composites on their mechanical, antibacterial, and physicochemical properties.

methodsA comprehensive search of PubMed, Scopus, and Web of Science databases was conducted in March 2025 using the following keywords: resin, composite, and chitosan. The inclusion criteria comprised in vitro studies in dentistry evaluating chitosan as a composite additive with full-text availability in English. Data extraction and quality assessment were performed independently by multiple reviewers using standardized tools, and study quality was assessed based on predefined criteria.

resultsSeventeen studies met the inclusion criteria. Chitosan concentrations in the composites ranged from 0.25 wt% to 20 wt%. Antibacterial activity was confirmed in six studies, especially against

conclusionChitosan-modified dental resin composites exhibit promising antibacterial and mechanical enhancements at low concentrations. However, higher chitosan levels may compromise certain mechanical and adhesive properties. These findings suggest a need for standardized methodologies and further research on long-term clinical implications and fluoride release.

Indexed as

Acrylic ResinsAnti-Bacterial AgentsChitosanComposite ResinsHumansPolyurethanesAcrylic ResinsAnti-Bacterial AgentsChitosanComposite Dental ResinComposite ResinsPolyurethanesantibacterialchitosanmechanical propertiesresin composite

Identifiers

PMID40422789
PMCPMC12113295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.