Evidence map›Paper›PMID 40422777›Full record

ArticleMarine drugs2025

Bioassay-Guided Procedure Coupled with HR-ESIMS Dereplication for Isolation of Antiproliferative Bromo-Tyramine Derivative from

Germana Esposito, Maria Ponticelli, Luigi Milella, Ludovica Lela, Roberta Teta, Joseph R Pawlik, Daniela Russo, Valeria Costantino

Abstract read
In one paragraph

Article in Marine drugs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Germana EspositoThe Blue Chemistry Lab, Department of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, 80131 Napoli, Italy.ORCID 0000-0001-9619-7511
Maria PonticelliDepartment of Biochemical Pharmacology & Drug Design, Institute of Molecular Biology "Roumen Tsanev", Bulgarian Academy of Sciences (BAS), Acad. G. Bonchev Str., bl. 21, 1113 Sofia, Bulgaria.ORCID 0000-0002-2145-0284
Luigi MilellaDepartment of Health Science, University of Basilicata, Via dell'Ateneo Lucano 10, 85100 Potenza, Italy.ORCID 0000-0002-5874-1237
Ludovica LelaDepartment of Health Science, University of Basilicata, Via dell'Ateneo Lucano 10, 85100 Potenza, Italy.ORCID 0000-0001-7011-7288
Roberta TetaThe Blue Chemistry Lab, Department of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, 80131 Napoli, Italy.ORCID 0000-0003-0817-7743
Joseph R PawlikDepartment of Biology and Marine Biology, Center for Marine Science, University of North Carolina Wilmington, 5600 Marvin K Moss Lane, Wilmington, NC 28409, USA.ORCID 0000-0002-8559-8456
Daniela RussoDepartment of Health Science, University of Basilicata, Via dell'Ateneo Lucano 10, 85100 Potenza, Italy.ORCID 0000-0002-3086-784X
Valeria CostantinoThe Blue Chemistry Lab, Department of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, 80131 Napoli, Italy.ORCID 0000-0001-8723-9505

Funding

NBFC PNRR Missione 4 Component 2 CN00000033
6 · The paper itself

Abstract

The marine environment is vital for sustaining life on Earth and offers a significant, untapped source of bioresources that could enhance the blue economy. The present investigation used our protocol to quickly identify bioactive molecules in

Indexed as

Antineoplastic AgentsTyramineAnimalsApoptosisBiological AssayCell ProliferationHep G2 CellsHumansSpectrometry, Mass, Electrospray IonizationAntineoplastic AgentsTyramineantiproliferative activityAplysina cauliformisapoptosisblue bioeconomyblue growthmarine bromo-tyramine analogN,N,N-trimethyl-3,5-dibromotyramine

Identifiers

PMID40422777
PMCPMC12113023

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.