Evidence map›Paper›PMID 40422593›Full record

ArticleDiseases (Basel, Switzerland)2025

Effects of Sex and Race on Epidemiology and Comorbidities of Patients with Irritable Bowel Syndrome: A Rome III Era Retrospective Study.

Jacqueline Liu, Kathleen Cheng, Yu Lu, Howard Cabral, Horst Christian Weber

Abstract read
In one paragraph

Article in Diseases (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jacqueline LiuDepartment of Medicine, Boston Medical Center, Boston, MA 02118, USA.
Kathleen ChengDepartment of Medicine, Boston Medical Center, Boston, MA 02118, USA.ORCID 0009-0000-4102-4699
Yu LuDepartment of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA.
Howard CabralDepartment of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA.ORCID 0000-0002-1185-8331
Horst Christian WeberDepartment of Medicine, Boston Medical Center, Boston, MA 02118, USA.ORCID 0000-0001-9005-6988

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIrritable bowel syndrome (IBS) is a prevalent disorder of gut-brain interaction (DGBI) with a negative impact on quality of life and healthcare expenditure. This study aimed to investigate sex-based differences in a large cohort of IBS patients from a multiracial safety-net hospital.

methodsAn electronic query was performed using the International Classification of Diseases, 9th Revision (ICD-9) coding to identify 740 outpatients with IBS between 1 January 2005 and 30 September 2007. Demographic data and ICD-9 coded comorbidities were extracted from electronic records. Data analysis used descriptive statistics and multiple logistic regression analyses.

resultsComorbid anxiety and depression were significantly more prevalent in female patients (A:24%,

conclusionsSignificant sex-based and racial/ethnic differences were identified related to body mass index (BMI), age, and IBS subtypes in this study. Comorbid mood disorders occurred significantly more frequently in female patients, and risk factors for comorbid depression included female sex, older age, and obesity but not race/ethnicity.

Indexed as

anxietycomorbiditiesdepressioneating disordersirritable bowel syndromeracial differencessex

Identifiers

PMID40422593
PMCPMC12110308

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.