Evidence map›Paper›PMID 40422511›Full record

ArticleCurrent oncology (Toronto, Ont.)2025

The Application Effect of Endoscopic Thyroidectomy via the Gasless Unilateral Axillary Approach in Thyroid Cancer and Its Impact on Postoperative Stress Response.

Jinliang Jia, Jihua Han, Rui Pang, Wen Bi, Bo Liu, Ruinan Sheng, Lingyu Kong

Abstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jinliang JiaDepartment of Head and Neck Surgery, Harbin Medical University Cancer Hospital, Harbin 150081, China.
Jihua HanDepartment of Head and Neck Surgery, Harbin Medical University Cancer Hospital, Harbin 150081, China.
Rui PangDepartment of Head and Neck Surgery, Harbin Medical University Cancer Hospital, Harbin 150081, China.
Wen BiDepartment of Head and Neck Surgery, Harbin Medical University Cancer Hospital, Harbin 150081, China.
Bo LiuDepartment of Head and Neck Surgery, Harbin Medical University Cancer Hospital, Harbin 150081, China.
Ruinan ShengDepartment of Head and Neck Surgery, Harbin Medical University Cancer Hospital, Harbin 150081, China.
Lingyu KongDepartment of Head and Neck Surgery, Harbin Medical University Cancer Hospital, Harbin 150081, China.

Funding

Beijing Medical Award Foundation: The role and molecular mechanism of Ang1/Tie2 signaling pathway in the induction of thyroid cancer in Hashimoto's thyroiditis YXJL-2023-0028-0052
6 · The paper itself

Abstract

objectiveThis study aims to evaluate the application effect of endoscopic thyroidectomy via the gasless unilateral axillary (GUA) approach in thyroid cancer and its impact on the postoperative stress response.

methodsNinety-four thyroid cancer patients were enrolleod and assigned into the open group (underwent conventional-open-anterior-cervical-approach thyroidectomy) and the endoscopic group (underwent GUA endoscopic thyroidectomy) (n = 47). Perioperative indicators between the two groups were compared. Thyroid function parameters [total triiodothyronine (TT3), total thyroxine (TT4), free triiodothyronine (FT3), free thyroxine (FT4), and thyroid-stimulating hormone (TSH)] were measured preoperatively and on postoperative day 2. Inflammatory markers [interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α)] and stress-related hormones [norepinephrine (NE) and cortisol (Cor)] were evaluated preoperatively and on postoperative day 1. The aesthetic appearance of the incision was evaluated at 1 and 3 months postoperatively using the Vancouver Scar Scale (VSS). Postoperative complications were also compared between the two groups.

resultsThe endoscopic group exhibited less intraoperative blood loss, reduced postoperative drainage, a lower pain degree on 1 day postoperatively, a shorter hospitalization time, and a longer surgical time versus the open group (

conclusionsEndoscopic thyroidectomy by a GUA offers notable advantages over the conventional-open-anterior-cervical-approach thyroidectomy, including reduced intraoperative blood loss, less postoperative drainage, and a lower postoperative stress response. This approach also results in improved cosmetic outcomes, making it a promising alternative for thyroid cancer surgery.

Indexed as

EndoscopyPostoperative ComplicationsThyroidectomyThyroid NeoplasmsAdultAxillaFemaleHumansMaleMiddle AgedStress, Physiologicalaxillary approachgasless endoscopic thyroidectomyparathyroid functionstress responsethyroid cancer

Identifiers

PMID40422511
PMCPMC12110371

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.