Evidence map›Paper›PMID 40422363›Full record

ReviewGels (Basel, Switzerland)2025

Multifunctional Janus Hydrogels: Surface Design Strategies for Next-Generation Clinical Solutions.

Taoxu Yan, Junyao Cheng, Haoming Liu, Yifan Wang, Chuyue Zhang, Da Huang, Jianheng Liu, Zheng Wang

Abstract readReview
In one paragraph

Review in Gels (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Taoxu YanDepartment of Orthopedics, Chinese PLA General Hospital, Beijing 100853, China.
Junyao ChengDepartment of Orthopedics, Chinese PLA General Hospital, Beijing 100853, China.
Haoming LiuDepartment of Orthopedics, Chinese PLA General Hospital, Beijing 100853, China.ORCID 0009-0009-1658-8287
Yifan WangDepartment of Orthopedics, Chinese PLA General Hospital, Beijing 100853, China.
Chuyue ZhangDepartment of Orthopedics, Chinese PLA General Hospital, Beijing 100853, China.ORCID 0009-0007-6353-5650
Da HuangCollege of Biological Science and Engineering, Fuzhou University, Fuzhou 350108, China.ORCID 0000-0003-3621-5233
Jianheng LiuDepartment of Orthopedics, Chinese PLA General Hospital, Beijing 100853, China.
Zheng WangDepartment of Orthopedics, Chinese PLA General Hospital, Beijing 100853, China.

Funding

The National Natural Science Foundation of China 82172392 and 82372499
6 · The paper itself

Abstract

Janus hydrogels, distinguished by their dual-sided structure with distinct physical and chemical properties, have garnered significant attention in the medical field, particularly for applications in drug delivery, tissue engineering, and wound healing. Their ability to simultaneously perform multiple functions, such as targeted drug release and biomimetic tissue interaction, positions them as a promising platform for advanced therapeutic strategies. The growing interest in these hydrogels is primarily driven by their multifunctionality and capacity to address complex biological needs. This review delves into the design, fabrication methods, and applications of Janus hydrogels in medicine, focusing on their potential to overcome the limitations of conventional therapies and providing a comprehensive overview of their role in contemporary biomedical applications.

Indexed as

hemostasisJanus hydrogelsorthopedic repairsmart medical systemstissue engineering

Identifiers

PMID40422363
PMCPMC12110767

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.