Evidence map›Paper›PMID 40422355›Full record

ArticleGels (Basel, Switzerland)2025

Three-Dimensional Gel Dosimetry in a Simulated Postmastectomy with Expandable Prosthesis Radiotherapy.

Juliana Fernandes Pavoni, Jessica Caroline Lizar, Leandro Frederiche Borges, Patricia Nicolucci, Yanai Krutman, Oswaldo Baffa

Abstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Juliana Fernandes PavoniDepartment of Physics, Faculty of Philosophy, Sciences and Letters of Ribeirão Preto, University of São Paulo, Ribeirão Preto 14040-901, SP, Brazil.ORCID 0000-0002-1647-8231
Jessica Caroline LizarDepartment of Physics, Faculty of Philosophy, Sciences and Letters of Ribeirão Preto, University of São Paulo, Ribeirão Preto 14040-901, SP, Brazil.
Leandro Frederiche BorgesRadiotherapy Sector, Clinical Hospital of the Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto 14048-900, SP, Brazil.
Patricia NicolucciDepartment of Physics, Faculty of Philosophy, Sciences and Letters of Ribeirão Preto, University of São Paulo, Ribeirão Preto 14040-901, SP, Brazil.ORCID 0000-0001-6501-1489
Yanai KrutmanSoroka Medical Center, Radiotherapy Department, Institute of Oncology, Beer Sheva 8410501, Israel.
Oswaldo BaffaDepartment of Physics, Faculty of Philosophy, Sciences and Letters of Ribeirão Preto, University of São Paulo, Ribeirão Preto 14040-901, SP, Brazil.ORCID 0000-0002-0622-2814

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 001Fundação de Amparo à Pesquisa do Estado de São Paulo 2013/07699-0, 2015-18221-9, 2018/05982-0 and 2021/02254-6National Council for Scientific and Technological Development 305827/2023-5 and 304921/2021-1.
6 · The paper itself

Abstract

Postmastectomy radiation therapy (PMRT) is an adjuvant treatment for breast cancer. Some mastectomized women undergoing PMRT can have breast reconstruction with expander implant reconstruction. However, the expander implant contains a magnetic metal port for its inflation, and in patients with a high risk of recurrence, the PMRT is performed before the expander replacement. The difficulties in radiation treatment near high-Z metals are mainly due to dose alterations around them. Therefore, this study proposes using a realistic breast phantom and gel dosimetry to investigate the effects of the metallic parts of the expandable prosthesis on the 3D delivery of the treatment. A conformal radiation treatment was planned and delivered to the gel phantom with the metal port. MAGIC-f gel was used with magnetic resonance imaging for dose assessment. The treatment plan dose distribution was compared to the measured dose distribution by gamma analysis (3%/3 mm/15% threshold). A significant gamma fail region was found near the metal port, corresponding to a dose reduction of approximately 5%. This underdose is within the tolerance threshold for dose heterogeneity established by the International Commission on Radiation Units (ICRU), but should be considered when treating these patients.

Indexed as

3D dosimetrybreast cancerexpandable prosthesisgel dosimetryMAGIC-f gelradiotherapy

Identifiers

PMID40422355
PMCPMC12111075

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.