Evidence map›Paper›PMID 40422354›Full record

ArticleGels (Basel, Switzerland)2025

Novel Gels for Post-Piercing Care: Evaluating the Efficacy of Pranoprofen Formulations in Reducing Inflammation.

Negar Ahmadi, Maria Rincón, Mireia Mallandrich, Joaquim Suñer-Carbó, Lilian Sosa, Mireya Zelaya, Sergio Martinez-Ruiz, Cecilia Cordero, Ana C Calpena

Abstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Negar AhmadiDepartment of Pharmacy, Pharmaceutical Technology and Physical Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona, Av. Joan XXIII 27-31, 08028 Barcelona, Spain.
Maria RincónDepartment of Materials Science and Physical Chemistry, Faculty of Chemistry, University of Barcelona, C. Martí i Franquès 1-11, 08028 Barcelona, Spain.ORCID 0009-0002-9012-0008
Mireia MallandrichDepartment of Pharmacy, Pharmaceutical Technology and Physical Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona, Av. Joan XXIII 27-31, 08028 Barcelona, Spain.ORCID 0000-0001-9316-8459
Joaquim Suñer-CarbóDepartment of Pharmacy, Pharmaceutical Technology and Physical Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona, Av. Joan XXIII 27-31, 08028 Barcelona, Spain.ORCID 0000-0002-9238-187X
Lilian SosaCentro Experimental en Biociencia (CENBIO), Facultad de Ciencias Químicas y Farmacia, Universidad Nacional Autónoma de Honduras (UNAH), Tegucigalpa 11101, Honduras.ORCID 0000-0001-8148-9482
Mireya ZelayaLaboratorio de Técnicas Histológicas, Facultad de Ciencias, Universidad Nacional Autónoma de Honduras (UNAH), Tegucigalpa 11101, Honduras.
Sergio Martinez-RuizDepartament de Bioquímica i Fisiologia, Facultat de Farmàcia i Ciències de l'Alimentació, University of Barcelona, 08028 Barcelona, Spain.ORCID 0000-0001-7394-3438
Cecilia CorderoDepartament de Bioquímica i Fisiologia, Facultat de Farmàcia i Ciències de l'Alimentació, University of Barcelona, 08028 Barcelona, Spain.
Ana C CalpenaDepartment of Pharmacy, Pharmaceutical Technology and Physical Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona, Av. Joan XXIII 27-31, 08028 Barcelona, Spain.ORCID 0000-0002-4989-4821

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mild to moderate pain for a few hours to several days post-piercing is normal, and the pain is usually accompanied by swelling, redness, and warmth due to the inflammatory response. Cool compresses and over-the-counter analgesics (e.g., NSAIDs) can ease mild discomfort. However, oral NSAIDs may have systemic side effects; for this reason, we propose a topical anti-inflammatory approach. Four pranoprofen-loaded gels were created using different gelling agents: Sepigel

Indexed as

HET-CAM testinflammation reductionNipagin (methyl 4-hydroxybenzoate)Nipasol (propyl 4-hydroxybenzoate)NSAIDpranoprofen (PF)topical gels

Identifiers

PMID40422354
PMCPMC12110840

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.