Evidence map›Paper›PMID 40422348›Full record

ArticleGels (Basel, Switzerland)2025

Easy-to-Apply Hydrogel Patch for Field Treatment and Monitoring of Equine Wounds.

María Emilia Zambroni, Patricia A Bertone, Ana Lucía Cabral, Andrés S Boatti, Silvia V Romanini, Sol R Martínez, María Lorena Gómez

Abstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

María Emilia ZambroniInstituto de Investigaciones en Tecnologías Energéticas y Materiales Avanzados (IITEMA), Universidad Nacional de Río Cuarto and Consejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET), Campus Universitario, Río Cuarto 5800, Argentina.ORCID 0009-0004-3427-6694
Patricia A BertoneDepartamento de Clínica Animal, Facultad de Agronomía y Veterinaria, Universidad Nacional de Río Cuarto, Campus Universitario, Río Cuarto 5800, Argentina.ORCID 0000-0003-0653-7549
Ana Lucía CabralDepartamento de Patología Animal, Facultad de Agronomía y Veterinaria, Universidad Nacional de Río Cuarto, Campus Universitario, Río Cuarto 5800, Argentina.ORCID 0009-0008-1135-6113
Andrés S BoattiDepartamento de Clínica Animal, Facultad de Agronomía y Veterinaria, Universidad Nacional de Río Cuarto, Campus Universitario, Río Cuarto 5800, Argentina.ORCID 0000-0003-3290-7953
Silvia V RomaniniDepartamento de Patología Animal, Facultad de Agronomía y Veterinaria, Universidad Nacional de Río Cuarto, Campus Universitario, Río Cuarto 5800, Argentina.ORCID 0009-0004-0421-8063
Sol R MartínezInstituto de Investigaciones en Tecnologías Energéticas y Materiales Avanzados (IITEMA), Universidad Nacional de Río Cuarto and Consejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET), Campus Universitario, Río Cuarto 5800, Argentina.ORCID 0000-0002-0612-3605
María Lorena GómezInstituto de Investigaciones en Tecnologías Energéticas y Materiales Avanzados (IITEMA), Universidad Nacional de Río Cuarto and Consejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET), Campus Universitario, Río Cuarto 5800, Argentina.ORCID 0000-0002-3542-1038

Funding

Agencia Nacional de Promoción Científica y Tecnológica 00492/2021Agencia Nacional de Promoción Científica y Tecnológica 03398/2020Consejo Nacional de Investigación Científica y Tecnológica PIP 11220200101845COUniversidad Nacional de Río Cuarto PPI 2023-2025
6 · The paper itself

Abstract

The cicatrization process, which is critical to equine health, directly affects overall well-being by preventing infection, minimizing tissue damage, and restoring optimal function. Herein, we present a case of a 5-year-old sorrel mare with a torn skin wound on the dorsal aspect of the metatarsal region of the left hind limb, treated locally with an antibiotic-free transparent hydrogel-based patch while monitoring its healing process. The patch induced pink granulation tissue in the treated area after 42 days, while keloid formation was observed in the untreated area. Wound measurements showed a reduction over time with patch treatment, with complete healing achieved at 116 days. Capillary formation and a velvety appearance were observed on day 80. Histological analysis revealed mature granulation tissue, fibrocyte formation, abundant capillaries, organized collagen fibrils, and development of type III collagen in the treated area. Interestingly, no inflammatory response was observed during treatment. The hydrogel patch not only accelerated healing, but also controlled excessive granulation tissue formation. This treatment represents an innovative approach to equine wound management that updates applications for owners while reducing costs.

Indexed as

collagenequinehydrogeltorn woundwound healing patches

Identifiers

PMID40422348
PMCPMC12111212

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.