Evidence map›Paper›PMID 40422204›Full record

ArticleCells2025

Use of Tissue Specimens from Stereotactic Biopsies for Patient-Derived GBM Organoid-Based Drug Testing.

Amélie Wöllner, Adrian Paul, Maddalena Arquilla, Junguo Cao, Catharina Lotsch, Gerhard Jungwirth, Lena Jassowicz, Andreas von Deimling, Andreas W Unterberg, Sandro M Krieg and 3 more

Abstract read
In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Amélie WöllnerDivision of Experimental Neurosurgery, Department of Neurosurgery, Medical Faculty of Heidelberg, University of Heidelberg, 69120 Heidelberg, Germany.ORCID 0009-0004-1272-7263
Adrian PaulDivision of Experimental Neurosurgery, Department of Neurosurgery, Medical Faculty of Heidelberg, University of Heidelberg, 69120 Heidelberg, Germany.
Maddalena ArquillaDivision of Experimental Neurosurgery, Department of Neurosurgery, Medical Faculty of Heidelberg, University of Heidelberg, 69120 Heidelberg, Germany.
Junguo CaoDivision of Experimental Neurosurgery, Department of Neurosurgery, Medical Faculty of Heidelberg, University of Heidelberg, 69120 Heidelberg, Germany.
Catharina LotschDivision of Experimental Neurosurgery, Department of Neurosurgery, Medical Faculty of Heidelberg, University of Heidelberg, 69120 Heidelberg, Germany.ORCID 0009-0005-5899-2609
Gerhard JungwirthDivision of Experimental Neurosurgery, Department of Neurosurgery, Medical Faculty of Heidelberg, University of Heidelberg, 69120 Heidelberg, Germany.ORCID 0000-0001-7571-8947
Lena JassowiczDivision of Experimental Neurosurgery, Department of Neurosurgery, Medical Faculty of Heidelberg, University of Heidelberg, 69120 Heidelberg, Germany.ORCID 0009-0009-1352-6443
Andreas von DeimlingDepartment of Neuropathology, Medical Faculty of Heidelberg, University of Heidelberg, 69120 Heidelberg, Germany.
Andreas W UnterbergDivision of Experimental Neurosurgery, Department of Neurosurgery, Medical Faculty of Heidelberg, University of Heidelberg, 69120 Heidelberg, Germany.
Sandro M KriegDivision of Experimental Neurosurgery, Department of Neurosurgery, Medical Faculty of Heidelberg, University of Heidelberg, 69120 Heidelberg, Germany.
Martin JakobsDivision for Stereotactic Neurosurgery, Department of Neurosurgery, Medical Faculty of Heidelberg, University of Heidelberg, 69120 Heidelberg, Germany.ORCID 0000-0002-6104-8898
Rolf WartaDivision of Experimental Neurosurgery, Department of Neurosurgery, Medical Faculty of Heidelberg, University of Heidelberg, 69120 Heidelberg, Germany.ORCID 0000-0003-2821-4361
Christel Herold-MendeDivision of Experimental Neurosurgery, Department of Neurosurgery, Medical Faculty of Heidelberg, University of Heidelberg, 69120 Heidelberg, Germany.ORCID 0000-0002-1915-745X

Funding

Deutsche Forschungsgemeinschaft 404521405Dietmar Hopp Stiftung
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Brain NeoplasmsGlioblastomaOrganoidsStereotaxic TechniquesBiopsyDrug Screening Assays, AntitumorHumansglioblastomapatient-derived tumor organoidsprecision medicinestereotactic biopsy

Identifiers

PMID40422204
PMCPMC12109714

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.