Evidence map›Paper›PMID 40422184›Full record

ArticleCells2025

Identification of Prognostic Biomarkers of Ovarian High-Grade Serous Carcinoma: A Preliminary Study Using Spatial Transcriptome Analysis and Multispectral Imaging.

Haeyoun Kang, Je-Gun Joung, Hyun Park, Min Chul Choi, Doohyun Koh, Ju-Yeon Jeong, Jimin Lee, Sook-Young Kim, Daun Jung, Sohyun Hwang and 1 more

Abstract read
In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Haeyoun KangDepartment of Pathology, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam 13496, Republic of Korea.ORCID 0000-0002-8980-7702
Je-Gun JoungDepartment of Biomedical Science, CHA University, Seongnam 13496, Republic of Korea.
Hyun ParkDepartment of Gynecological Oncology, Comprehensive Gynecologic Cancer Center, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam 13496, Republic of Korea.
Min Chul ChoiDepartment of Obstetrics and Gynecology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Republic of Korea.ORCID 0000-0003-4509-6731
Doohyun KohDepartment of Biomedical Science, CHA University, Seongnam 13496, Republic of Korea.
Ju-Yeon JeongCHA Future Medicine Research Institute, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam 13496, Republic of Korea.
Jimin LeeCHA Future Medicine Research Institute, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam 13496, Republic of Korea.
Sook-Young KimCHA Future Medicine Research Institute, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam 13496, Republic of Korea.
Daun JungCHA Biomedical Research Institute, CHA Bundang Medical Center, Seongnam 13496, Republic of Korea.
Sohyun HwangDepartment of Pathology, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam 13496, Republic of Korea.ORCID 0000-0003-2461-6806
Hee Jung AnDepartment of Pathology, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam 13496, Republic of Korea.

Funding

Korea Health Industry Development Institute HI16C1559Korea Health Industry Development Institute HI21C0977Ministry of Science and ICT NRF-2019R1A6A1A03032888Ministry of Science and ICT NRF-2022R1A2C109179712Ministry of Science and ICT NRF-2022R1F1A1071285
6 · The paper itself

Abstract

Ovarian cancer is a lethal malignancy, with most patients initially responding to chemotherapy but frequently experiencing recurrence. Previous studies primarily examined tumor characteristics using limited genetic markers or bulk RNA sequencing. Here, we used spatial transcriptomics via the GeoMx

Indexed as

Biomarkers, TumorCystadenocarcinoma, SerousGene Expression ProfilingOvarian NeoplasmsTranscriptomeAgedFemaleGene Expression Regulation, NeoplasticHumansMiddle AgedNeoplasm Recurrence, LocalPrognosisBiomarkers, Tumorbiomarkerscancer recurrenceovarian cancerspatial transcriptomicstumor microenvironment

Identifiers

PMID40422184
PMCPMC12110039

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.