Evidence map›Paper›PMID 40422092›Full record

ArticleBiomimetics (Basel, Switzerland)2025

Topologically Optimized Anthropomorphic Prosthetic Limb: Finite Element Analysis and Mechanical Evaluation Using Plantogram-Derived Foot Pressure Data.

Ioannis Filippos Kyriakidis, Nikolaos Kladovasilakis, Marios Gavriilopoulos, Dimitrios Tzetzis, Eleftheria Maria Pechlivani, Konstantinos Tsongas

Abstract read
In one paragraph

Article in Biomimetics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ioannis Filippos KyriakidisAdvanced Materials and Manufacturing Technologies Laboratory, Department of Industrial Engineering and Management, School of Engineering, International Hellenic University, 57001 Thessaloniki, Greece.
Nikolaos KladovasilakisInformation Technologies Institute/Centre for Research and Technology Hellas, 57001 Thessaloniki, Greece.ORCID 0000-0002-6594-8770
Marios GavriilopoulosAdvanced Materials and Manufacturing Technologies Laboratory, Department of Industrial Engineering and Management, School of Engineering, International Hellenic University, 57001 Thessaloniki, Greece.
Dimitrios TzetzisDigital Manufacturing and Materials Characterization Laboratory, School of Science and Technology, International Hellenic University, 57001 Thermi, Greece.ORCID 0000-0001-5006-5759
Eleftheria Maria PechlivaniInformation Technologies Institute/Centre for Research and Technology Hellas, 57001 Thessaloniki, Greece.ORCID 0000-0001-6385-2815
Konstantinos TsongasAdvanced Materials and Manufacturing Technologies Laboratory, Department of Industrial Engineering and Management, School of Engineering, International Hellenic University, 57001 Thessaloniki, Greece.ORCID 0000-0001-7050-5432

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of prosthetic limbs has benefited individuals who suffered amputations due to accidents or medical conditions. During the development of conventional prosthetics, several challenges have been observed regarding the functional limitations, the restricted degrees of freedom compared to an actual human limb, and the biocompatibility issues between the surface of the prosthetic limb and the human tissue or skin. These issues could result in mobility impairments due to failed mimicry of the actual stress distribution, causing discomfort, chronic pain, and tissue damage or possible infections. Especially in cases where underlying conditions exist, such as diabetes, possible trauma, or vascular disease, a failed adaptation of the prosthetic limb could lead to complete abandonment of the prosthetic part. To address these challenges, the insertion of topologically optimized parts with a biomimetic approach has allowed the optimization of the mimicry of the complex functionality behavior of the natural body parts, allowing the development of lightweight efficient anthropomorphic structures. This approach results in unified stress distribution, minimizing the practical limitations while also adding an aesthetic that aids in reducing any possible symptoms related to social anxiety and impaired social functioning. In this paper, the development of a novel anthropomorphic designed prosthetic foot with a novel Thermoplastic Polyurethane-based composite (TPU-Ground Tire Rubber 10 wt.%) was studied. The final designs contain advanced sustainable polymeric materials, gyroid lattice geometries, and Finite Element Analysis (FEA) for performance optimization. Initially, a static evaluation was conducted to replicate the phenomena at the standing process of a conventional replicated above-knee prosthetic. Furthermore, dynamic testing was conducted to assess the mechanical responses to high-intensity exercises (e.g., sprinting, jumping). The evaluation of the dynamic mechanical response of the prosthetic limb was compared to actual plantogram-derived foot pressure data during static phases (standing, light walking) and dynamic phenomena (sprinting, jumping) to address the optimal geometry and density, ensuring maximum compatibility. This innovative approach allows the development of tailored prosthetic limbs with optimal replication of the human motion patterns, resulting in improved patient outcomes and higher success rates. The proposed design presented hysteretic damping factor and energy absorption efficiency adequate for load handling of intense exercises (0.18 loss factor, 57% energy absorption efficiency) meaning that it is suitable for further research and possible upcycling.

Indexed as

anthropomorphic designbioinspired topology optimizationfinite element analysisground tire rubber compositesmechanical propertiesorthopedic biomechanicsTPU

Identifiers

PMID40422092
PMCPMC12108619

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.