ArticleBiosensors2025
Aptamer-Based Planar Electric Double-Layer Field-Effect Transistor: A Novel Approach for Sensitive Troponin I Sensing.
Article in Biosensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Recent approaches in the sensing strategy for the detection of cardiovascular disease biomarkers.RSC advances · 2026Review
- Review
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Authors and funding
2 authors.
Funding
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Abstract
This study introduces a cutting-edge, aptamer-based, planar electric, double-layer field-effect transistor (FET) system that offers both high sensitivity and specificity for the detection of troponin I (TnI). The proposed sensing platform leverages the signal amplification capabilities of FETs alongside the unique attributes of a planar electric double-layer design to address the limitations inherent in traditional ion-sensitive detectors, which are impacted by Debye length effects. By integrating TnI-specific aptamers, the system markedly enhances molecular recognition and transduction efficiency, achieving an impressive detection limit of 0.0001467 decade. Furthermore, the sensor demonstrates a strong exponential linear response across a clinically relevant concentration range of 1 ng/mL to 100 ng/mL. This innovative approach underscores the potential of electric double-layer FET systems to advance biomarker detection technologies for medical diagnostics and point-of-care applications.
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Registered trials
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