Evidence map›Paper›PMID 40421889›Full record

ArticleOrthopaedic surgery2025

One-Year Functional Outcomes Following Geriatric Hip Fracture: A Prospective Cohort Analysis.

Wei Zheng, Qianying Cai, Changqing Zhang, Shengbao Chen, Kai Fu

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Article in Orthopaedic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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5 authors.

Wei ZhengDepartment of Orthopedic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID https://orcid.org/0000-0002-5371-7000
Qianying CaiDepartment of Orthopedic Surgery, Shanghai Institute of Microsurgery on Extremities, Shanghai, China.
Changqing ZhangDepartment of Orthopedic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shengbao ChenDepartment of Orthopedic Surgery, Shanghai Institute of Microsurgery on Extremities, Shanghai, China.
Kai FuDepartment of Orthopedic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID https://orcid.org/0000-0002-8721-0734

Funding

Jiangxi Postgraduate Innovation Special Fund Project YC2022 - s231Jiangxi Provincial Natural Science Foundation 20224BAB216111Shanghai Municipal Health Commission, Capacity building for multidisciplinary cooperation in diagnosis and treatment of elderly hip fractures, Shanghai Jiao Tong University School of Medicine DLY201616Shanghai Municipal Health Commission Health Industry Clinical Research Project 20224Y0139Shanghai Shen Kang Hospital Development Center, Clinical Research Plan of SHDC SHDC2020CR6019
6 · The paper itself

Abstract

objectiveWith the characteristics of population change, geriatric hip fracture is increasing, accompanied by high morbidity and mortality rates. However, limited research has thoroughly investigated the postsurgery functional outcomes of hip fractures in the elderly population.

methodsThis study included 993 patients who underwent hip fracture surgery, drawn from a prospective cohort in China. Demographic and clinical data were collected for all participants. The cohort was randomly divided into training and validation sets (8:2). Least absolute shrinkage and selection operator (LASSO) regression and multivariable logistic regression analyses were employed to identify predictive factors for hip function at 12 months postoperatively. A nomogram was developed using R software and evaluated using concordance index (C-indexes), area under the curve (AUC), decision curve analysis (DCA), and calibration curves.

resultsPatients were divided into training (n = 794) and validation set (n = 199). Eight independent predictive variables for the poor functional outcome (Harris Hip Score < 80) after hip fracture include age (odds ratio [OR], 1.08; 95% confidence interval [CI], 1.04-1.12), hypertension history (OR, 2.53; 95% CI, 1.50-4.23), fracture type (OR, 0.28; 95% CI, 0.17-0.48), blood transfusion (OR, 2.30; 95% CI, 1.35-3.94), baseline PARKER score (OR, 0.85; 95% CI, 0.75-0.97), adverse events occurred within 12 months postoperatively (OR, 5.49; 95% CI, 2.30-13.08), transfer to the rehabilitation institution (OR, 3.22; 95% CI, 1.51-6.88), and time from surgery to weight-bearing (OR, 1.02; 95% CI, 1.01-1.03). The nomogram demonstrated excellent predictive ability in the training set (AUC = 0.853, [95% CI: 0.816-0.890]). Furthermore, according to the calibration curve, the model's prediction and actual observation were in good consistency, and the DCA curve demonstrated good clinical usefulness.

conclusionsThis study developed a personalized, predictive nomogram with eight risk factors for predicting 1-year functional outcomes in geriatric patients with hip fractures. Our model facilitates the early identification of high-risk patients and enables surgeons to implement timely preventive interventions.

Indexed as

Hip FracturesAgedAged, 80 and overChinaFemaleHumansMaleNomogramsProspective StudiesRecovery of FunctionRisk FactorsTreatment Outcomecohort studyfunctional outcomegeriatrichip fracturenomogram

Identifiers

PMID40421889
PMCPMC12214424

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.