Evidence map›Paper›PMID 40421700›Full record

ArticleInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2025

Inter-twin delivery interval and outcome of the second twin: A retrospective study.

Osnat Ezra, Liran Holtzman, Hila Lahav-Ezra, Shali Mazaki-Tovi, Eran Barzilay

Abstract read
In one paragraph

Article in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Inter-twin delivery interval and outcome of the second twin: A retrospective study.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Osnat EzraDepartment of Obstetrics and Gynecology, Sheba Medical Center, Tel-Hashomer, Israel.ORCID https://orcid.org/0000-0002-2041-1996
Liran HoltzmanDepartment of Obstetrics and Gynecology, Sheba Medical Center, Tel-Hashomer, Israel.
Hila Lahav-EzraDepartment of Obstetrics and Gynecology, Sheba Medical Center, Tel-Hashomer, Israel.
Shali Mazaki-ToviDepartment of Obstetrics and Gynecology, Sheba Medical Center, Tel-Hashomer, Israel.
Eran BarzilayDepartment of Obstetrics and Gynecology, Samson Assuta Ashdod University Hospital, Ashdod, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine the association between the inter-twin delivery interval and outcome of the second twin in a large sample.

methodsThis was a retrospective study at a single tertiary center between the years 2011 and 2021. The study included diamniotic twin pregnancies at ≥24 weeks of gestation that underwent a trial of vaginal delivery. A total of 1808 cases of twin pregnancies were included in the study. Cases were grouped according to inter-twin delivery interval of ≤15 min (n = 1676) or >15 min (n = 132). The neonatal outcome of the second twin was compared between the groups. In addition, we evaluated possible factors affecting the inter-twin delivery interval.

resultsUmbilical cord pH and base deficit were significantly lower and higher, respectively, for the second twin in the prolonged interval group; however, no difference was shown concerning neonatal composite outcome. In addition, a prolonged inter-twin interval was significantly associated with maternal age, body mass index, gestational age, labor induction, rupture of membranes duration, intrapartum fever, nighttime shift, birth weight of the second twin, twin birth weight ratio, and discordancy >20%. On the other hand, a short inter-twin interval was significantly associated with monochorionicity and neonatal intensive care unit admission.

conclusionsOur study showed no significant effect of inter-twin delivery interval on the composite outcome of the second twin. However, a prolonged inter-twin interval was associated with lower umbilical cord pH and higher base deficit.

Indexed as

Delivery, ObstetricPregnancy OutcomePregnancy, TwinTwinsAdultBirth WeightFemaleGestational AgeHumansHydrogen-Ion ConcentrationInfant, NewbornMaternal AgePregnancyRetrospective StudiesTime Factorsinter‐twin delivery intervalsecond twin outcometwins' delivery

Identifiers

PMID40421700
PMCPMC12553091

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.