SynthesisTropical medicine & international health : TM & IH2025
Effectiveness of health education in improving treatment adherence among patients with chronic communicable diseases: A systematic review and meta-analysis.
Synthesis in Tropical medicine & international health : TM & IH, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- [Interpretation of key updates of the 2026 version of the APASL clinical practice guidelines for the management of chronic hepatitis B].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2026Guideline
- APASL clinical practice guidelines on the management of chronic hepatitis B infection: a 2026 update.Hepatology international · 2026Guideline
- Effectiveness of health education in improving treatment adherence among patients with chronic communicable diseases: A systematic review and meta-analysis.Tropical medicine & international health : TM & IH · 2025Pooled it
- Spatial Transcriptomics in Thyroid Cancer: A PRISMA-Style Systematic Review of Platforms, Architecture, and Clinical Applications.Journal of clinical medicine · 2026Review
- Linking prevention and adherence: a behavioural study on treatment compliance to preventing TB transmission.IJTLD open · 2026Article
- [APASL clinical practice guidelines on the management of chronic hepatitis B infection: a 2026 update].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2026Article
- Barriers and Facilitators to the Use of Novel Injectable Lipid-Lowering Therapies in Patients with Dyslipidemia or Cardiovascular Disease: A Scoping Review.Medicina (Kaunas, Lithuania) · 2026Article
- Modern Management of CKM Syndrome: Use of GLP-1 Receptor Agonists in a Multidisciplinary Setting-Expert Group Recommendations from Kuwait.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2026Review
- Self-Perceptions of Aging in Older Adults: A Network Analysis of Clinical and Non-Clinical Samples.Brain sciences · 2026Article
- Yushida: an IoT-based smart injection system for long-term management of chronic diseases.Frontiers in digital health · 2026Review
- Barriers and Facilitators to Patient Education Among Nurses in Multicultural Hospital Settings: A Cross-Sectional Study.Nursing reports (Pavia, Italy) · 2025Article
- Clinical and Social Determinants of Quality of Life among People Living with HIV in Jodhpur, Rajasthan: A Cross-Sectional Study using the WHOQOL-HIV BREF.Indian journal of community medicine : official publication of Indian Association of Preventive & Social MedicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionChronic communicable diseases, such as tuberculosis, HIV, hepatitis B, and hepatitis C, remain major global health challenges. Effective treatment adherence is crucial for improving patient outcomes and health education plays a key role in enhancing adherence. However, evidence for the most effective educational interventions remains limited.
objectiveThis study aimed to evaluate the effectiveness of health education interventions in improving treatment adherence among patients with chronic communicable diseases.
methodsA systematic review and meta-analysis were conducted following the preferred item for systematic review and meta-analysis (PRISMA) guidelines. Comprehensive searches were performed in PubMed, CINAHL, Scopus, and the Web of Science for studies published between 2015 and 2024. Eligible studies included randomised controlled trials. Quality assessment was conducted using the Joanna Briggs Institute critical appraisal tools. Statistical analysis was performed using the Mantel-Haenszel method to estimate odds ratios (OR) and standardised mean differences (SMD) with 95% confidence intervals (CI) using a random effects model. Meta-regression was conducted to explore potential sources of heterogeneity.
resultsSeventeen studies involving 4,157 participants were included. Health education interventions significantly improved treatment adherence compared to usual care (OR 2.42; 95% CI: 1.58-3.72; p <0.0001). Subgroup analyses showed the highest effectiveness in remote-based interventions (OR 5.65; 95% CI: 2.37-13.47), among patients with tuberculosis (OR 6.52; 95% CI: 3.59-11.84), and in upper-middle-income countries (OR 4.54; 95% CI: 1.54-13.39). Meta-regression indicated that younger participant age and intervention type were significant moderators, with media-based and remote-based showing greater effectiveness.
conclusionHealth education interventions significantly improve treatment adherence among patients with chronic communicable diseases, particularly those with tuberculosis and hepatitis C. Remote-based models, such as mHealth platforms and digital reminders, demonstrate the highest effectiveness, especially in low- and middle-income countries where stigma and limited healthcare access remain key barriers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.