Evidence map›Paper›PMID 40421518›Full record

ArticleInternational health2026

A qualitative risk assessment of Crimean-Congo haemorrhagic fever in Nigeria: implications for One Health response.

Abiodun Egwuenu, Sunday Makama, Nasir Ahmed, Olanrewaju Igah, Gloria Nwiyi, Yetunde Abioye, Damilola Kolade, Chika Okpala, Chinenye Emelife, Oyeladun Okunromade and 6 more

Abstract read
In one paragraph

Article in International health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Abiodun EgwuenuNigeria Centre for Disease Control and Prevention, Abuja, FCT, 900108, Nigeria.ORCID 0000-0002-9369-4771
Sunday MakamaNational Veterinary Research Institute, Vom, Plateau State, 930101, Nigeria.ORCID 0000-0002-1582-6345
Nasir AhmedNigeria Centre for Disease Control and Prevention, Abuja, FCT, 900108, Nigeria.
Olanrewaju IgahNational Veterinary Research Institute, Vom, Plateau State, 930101, Nigeria.ORCID 0000-0003-0092-576X
Gloria NwiyiNigeria Centre for Disease Control and Prevention, Abuja, FCT, 900108, Nigeria.ORCID 0000-0001-8882-2647
Yetunde AbioyeNigeria Centre for Disease Control and Prevention, Abuja, FCT, 900108, Nigeria.ORCID 0000-0001-6091-200X
Damilola KoladeNigeria Centre for Disease Control and Prevention, Abuja, FCT, 900108, Nigeria.ORCID 0009-0003-6138-7384
Chika OkpalaFederal Ministry of Environment, 900108, Nigeria.
Chinenye EmelifeNigeria Centre for Disease Control and Prevention, Abuja, FCT, 900108, Nigeria.ORCID 0000-0002-3330-7178
Oyeladun OkunromadeNigeria Centre for Disease Control and Prevention, Abuja, FCT, 900108, Nigeria.ORCID 0000-0002-8242-8590
Elsie IloriNigeria Centre for Disease Control and Prevention, Abuja, FCT, 900108, Nigeria.ORCID 0000-0002-1731-2604
Jerry PantuvoUK Health Security Agency (UKHSA), 900108, Nigeria.ORCID 0009-0005-0141-1498
Emmanuel AgogoFIND, 1218, Switzerland.ORCID 0000-0002-3570-3254
Olusola ArunaUK Health Security Agency (UKHSA), 900108, Nigeria.ORCID 0000-0002-7879-634X
Chinwe Lucia OchuNigeria Centre for Disease Control and Prevention, Abuja, FCT, 900108, Nigeria.ORCID 0000-0002-0630-7332
Ifedayo M O AdetifaNigeria Centre for Disease Control and Prevention, Abuja, FCT, 900108, Nigeria.ORCID 0000-0003-2556-9407

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCrimean-Congo Haemorrhagic Fever (CCHF) is a severe tick-borne viral disease. Increasing cases in West Africa suggest potential undetected circulation in Nigeria.

methodsA One Health Joint Risk Assessment was conducted to identify transmission pathways and assess the likelihood and impact of human CCHF infections at the human-animal-environment interface in Nigeria. Risk framing involved developing structured questions for potential Crimean-Congo Haemorrhagic Fever virus (CCHFV) transmission scenarios. A scoping review was conducted and median seroprevalence values were reported. The likelihood, impact and data uncertainty for human infection scenarios were used for a qualitative estimation of risk.

resultsHuman contact with infected livestock during farming, veterinary practices and exposure to ticks was identified as a key infection route. Most cases in Nigeria (66.7%) were identified via serology, with a median human seroprevalence of 6.1% and cattle seroprevalence of 30.2%. CCHFV has been isolated from Rhipicephalus ticks. Four risk assessment questions were defined and focused on veterinarians, abattoir workers, herders, wildlife rangers and healthcare workers. Animal-related professions had a moderate likelihood of infection.

conclusionStrengthening One Health surveillance, vector control and multisector infection prevention is crucial to reducing the risk of CCHF and averting future outbreaks.

Indexed as

Hemorrhagic Fever, CrimeanOne HealthAnimalsCattleHemorrhagic Fever Virus, Crimean-CongoHumansLivestockNigeriaRisk AssessmentSeroepidemiologic StudiesTicksCrimean-Congo Haemorrhagic FeverNigeriaOne Healthrisk assessmentsurveillance

Identifiers

PMID40421518
PMCPMC12766461

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.