Evidence map›Paper›PMID 40421450›Full record

ArticleEJHaem2025

Teclistamab-Induced Remission of Chronic Immune Thrombocytopenia in a Patient With Multiple Myeloma.

Renata Quevedo-Salazar, José Miguel Yáñez-Reyes, Elías Eugenio González-López, Ana Varela-Constantino, Andrés Gómez-De León, Xitlaly Judith González-Leal, David Gómez-Almaguer

Abstract read
In one paragraph

Article in EJHaem, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Renata Quevedo-SalazarTecnologico de Monterrey Internal Medicine, Monterrey Nuevo Leon Mexico.ORCID https://orcid.org/0000-0002-6149-2243
José Miguel Yáñez-ReyesHospital Universitario Dr. Jose Eleuterio Gonzalez Universidad Autonoma de Nuevo Leon, Hematology Monterrey Nuevo Leon Mexico.ORCID https://orcid.org/0009-0005-0484-1207
Elías Eugenio González-LópezClinica Gomez Almaguer, Hematology Monterrey Nuevo Leon Mexico.ORCID https://orcid.org/0000-0001-9674-0940
Ana Varela-ConstantinoClinica Gomez Almaguer, Hematology Monterrey Nuevo Leon Mexico.ORCID https://orcid.org/0000-0001-7952-6731
Andrés Gómez-De LeónClinica Gomez Almaguer, Hematology Monterrey Nuevo Leon Mexico.ORCID https://orcid.org/0000-0001-6904-9345
Xitlaly Judith González-LealTecnologico de Monterrey Internal Medicine, Monterrey Nuevo Leon Mexico.ORCID https://orcid.org/0000-0003-2663-5728
David Gómez-AlmaguerClinica Gomez Almaguer, Hematology Monterrey Nuevo Leon Mexico.ORCID https://orcid.org/0000-0002-0460-6427

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the case of a 76-year-old woman with refractory immune thrombocytopenia (ITP) and multiple myeloma (MM) who achieved remission of both conditions following teclistamab treatment. After failing multiple ITP therapies, her platelet count continued to decline. Initiation of teclistamab led to a rapid and sustained platelet increase, alongside MM response with measurable residual disease (MRD) negativity. Notably, remission was achieved after only four full doses, and the patient has remained in complete remission since. This case highlights teclistamab as a potential treatment for refractory ITP, suggesting a novel role for B-cell maturation antigen (BCMA)-targeted therapies in autoimmune diseases. Trial Registration: The authors have confirmed clinical trial registration is not needed for this submission.

Identifiers

PMID40421450
PMCPMC12104531

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.